The first mention of Hohenheim is in a donation of some land to Hirsau Abbey by Egilof von Hohenheim. The castle was sold by the von Hohenheim family in 1406, and passed to the Esslingen hospital in 1432. In 1676, it was bought by Immanuel von Garb, after whom it was known as Garbenhof for some time. As von Garb's granddaughter died without heirs in 1768, the estate fell into the possession of Charles Eugene, Duke of Württemberg. Charles Eugene made Hohenheim his main residence in 1772 and made major changes to the estate, turning it into a full sized Rococo manor. The gardens around the castle were also planned at this time. They featured pillars depicting the Roman gods Jupiter and a playhouse now used as a museum by the University of Hohenheim. The gardens continued to be maintained and many exotic plants were added. The Duke commissioned an extensive residential palace to be built on the grounds of Hohenheim in 1782 until construction halted in 1793 due to the Duke's death at Hohenheim. His brother, Duke Frederick II Eugene died in Hohenheim in 1797, afer which the estate land was rented out to tenants and the manor and gardens placed under the administration of the city of Stuttgart, falling into gradual decline. It was used as a military hospital in 1814. In 1818, King Wilhelm I of Württemberg and his wife Catherine founded the Agricultural Educational Testing and Model Institution, which was housed in a separate building on the castle and the Paracelsus School was housed in the east wing much later. During World War II, a wing of the castle was destroyed, but was rebuilt. In the 1970s, the castle was restored and modernized and the rococo plaster removed. The 1990s saw the return of this plaster to lock once again.
Current use
Today, the University of Hohenheim uses large portions of the castle grounds. The Horticulture and Agriculture Departments of the University have been found on the castle grounds since 1818. The Kavaliersbau Squire's lodge, the University of Hohenheim established a canteen in 1918 that was converted into a restaurant in 1958.
Friedrich Schiller visited and described the park of Schloss Hohenheim like so: "The nature that we find in the English system is no longer that which we had expected. It is inspired by the spirit and exalted by Art and Nature"