Human Proteome Folding Project
The Human Proteome Folding Project is a collaborative effort between New York University, the Institute for Systems Biology and the University of Washington, using the Rosetta software developed by the Rosetta Commons.
HPF Phase 1 applied Rosetta v4.2x software on the human genome and 89 others, starting in November 2004. Phase 1 ended in July 2006. HPF Phase 2 applies the Rosetta v4.8x software in higher resolution, "full atom refinement" mode, concentrating on cancer biomarkers, human secreted proteins and malaria.
Phase 1 ran on two distributed computing grids: on United Devices' grid.org, and on the World Community Grid, an IBM philanthropic initiative. Phase 2 of the project ran exclusively on the World Community Grid; it terminated in 2013 after more than 9 years of IBM involvement.
The Institute for Systems Biology will use the results of the computations within its larger research efforts.
, Human Proteome Folding Project Phase2, running under UD client softwarePublications
