Hydroxyacylglutathione hydrolase


In enzymology, a Hydroxyacylglutathione hydrolase is an enzyme that catalyzes the chemical reaction
Hence, this enzyme has two substrates, -S-lactoylglutathione and water, and two products, glutathione and a 2-hydroxy carboxylate. With the common substrate methylglyoxal, the product is D-lactate.
This enzyme belongs to the family of hydrolases, specifically the class of thioester lyases. This enzyme is commonly known as glyoxalase II. This enzyme participates in pyruvate metabolism.