Immune receptor
An immune receptor is a receptor, usually on a cell membrane, which binds to a substance and causes a response in the immune system.
Types
The main receptors in the immune system are pattern recognition receptors, Toll-like receptors, killer activated and killer inhibitor receptors, complement receptors, Fc receptors, B cell receptors and T cell receptors.Receptor | Bind to | Function |
pattern recognition receptors | pathogen-associated molecular patterns | Mediate cytokine production --> inflammation --> destroying pathogen |
killer activated and killer inhibitor receptors | Avails NK cells to identify abnormal host cells or inhibit inappropriate host cell destruction | |
complement receptors | complement proteins on e.g. microbes | Allow phagocytic and B cells to recognize microbes and immune complexes |
Fc receptors | epitope-antibody complexes | Stimulate phagocytosis |
B cell receptors | epitopes | B cell differentiation into plasma cells and proliferation |
T cell receptors | linear epitopes bound to MHC | Activate T cells |
Cytokine receptors | cytokines | regulation and co-ordination of immune responses |