In 521 BCE, Intaphrenes was sent as general at the head of an army by Darius I to eliminate Arakha, who allegedly had usurped the throne of Babylon as Nebuchadnezzar IV in 522 BCE. Babylon was taken without much fighting on November 27, 521 BCE, and as was customary in such cases, Arakha was mutilated and impaled with his followers.
Death
Intaphrenes was put to death after the insurrection for trying to enter the King's palace while he was lying with his wife. The seven noblemen who had toppled Bardiya had made an agreement that they could all visit the new king whenever they pleased, except when he was with his wife. One evening, Intaphrenes went to the palace to meet Darius, but was stopped by two officers who stated that Darius had retired for the night. Becoming enraged and insulted, Intaphrenes drew his sword and cut off the ears and noses of the two officers. While leaving the palace, he took the bridle from his horse, and tied the two officers together. The officers went to the king and showed him what Intaphrenes had done to them. Darius began to fear for his own safety; he thought that all seven noblemen had banded together to rebel against him and that the attack against his officers was the first sign of revolt. He sent a messenger to each of the noblemen, asking them if they approved of Intaphrenes's actions. They denied and disavowed any connection with Intaphrenes's actions, stating that they stood by their decision to appoint Darius as King of Kings. Taking precautions against further resistance, Darius sent soldiers to seize Intaphrenes, along with his son, family members, relatives and any friends who were capable of arming themselves. Darius believed that Intaphrenes was planning a rebellion, but when he was brought to the court, there was no proof of any such plan. Nonetheless, Darius killed Intaphrenes's entire family, excluding his wife's brother and son. She was asked to choose between her brother and son. She chose her brother to live. Her reasoning for doing so was that she could have another husband and another son, but she would always have but one brother. Darius was impressed by her response and spared both her brother's and her son's life. The name Intaphrenes was never mentioned again by Herodotus after Intaphrenes's death.