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Ipatasertib
Ipatasertib
is an
experimental
cancer drug
in
development
by
Roche
. It is a
small molecule
inhibitor
of
AKT
, which is a
key
component
of the
PI3K/AKT pathway
. It was
discovered
by
Array Biopharma
and is
currently
in phase
II
trials
for
treatment
of
breast cancer
.
In vitro
, ipatasertib showed
activity
against all three
isoforms
of
Akt
.