Sanford was born in Wellesley Hills, Massachusetts. After playing in the minor leagues for seven seasons, he made his major league debut with the Phillies on September 16, 1956 at the age of 27. Sanford made an immediate impact the following season when, he began the year with a 10-2 win-loss record to earn a spot on the National League team in the 1957 All-Star Game on July 9, 1957. He ended the season with a 19-8 win-loss record and a 3.08 earned run average along with a league-leading 188 strikeouts. His 19 victories were second only to the 21 wins by Warren Spahn. He also had 15 complete games on the season, including three shutouts. For his impressive performance, he was named the National League Rookie of the Year in. His next seven years would be extremely solid, but never quite as impressive as his rookie season; or according to some, he never improved much after it. After being traded to the Giants for the season, Sanford went 15-12 with a 3.16 ERA in 222 innings pitched and completed 10 games. That year, he started 31 games and made 36 appearances, 5 out of the bullpen. Sanford led the Giants to the 1962 National League pennant with 24 victories, second only to the 25 victories by Don Drysdale. He won 16 consecutive decisions from mid-June to mid-September and was named Player of the Month in August for his second straight 6-0 month. Only Rube Marquard, who won 19 straight games for the 1912 New York Giants, and Roy Face, who won 17 straight for the 1959 Pittsburgh Pirates have won more consecutive games in a single season during the modern era. Six pitchers have matched Sanford's 16-game streak. The Giants would face the New York Yankees in the World Series in the only post-season appearance of Sanford's career. Sanford made three starts for the club in the World Series. In Game 2, he pitched a three-hit shutout as the Giants beat the Yankees 2-0. He was supposed to start Game 5 October 9, but rain pushed it back a day, which bothered Sanford, who had psyched himself to pitch that day. Sanford gave up a three-run home run to Tom Tresh and a total of five runs in innings as the Giants lost 5-3. He pitched better in Game 7, allowing just one run in seven innings against the Yankees when Bill Skowron scored as Tony Kubek hit into a double play in the fifth inning. That run was enough, though, for the Yankees to win 1-0, behind a Ralph Terry shutout. Sanford finished second to Don Drysdale in the voting for the 1962 Cy Young Award. After he left the Giants, his best seasons were behind him. He ended his playing career with the Kansas City Athletics on August 6, at the age of 38. However, Sanford remained in the major leagues for two more seasons as the pitching coach of the – Cleveland Indians. Working on the staff of Alvin Dark, his manager with the 1962 Giants and 1967 Athletics, Sanford's first season saw the 1968 Indians compile a staff earned run average of 2.66. Throughout baseball, 1968 was known as "The Year of the Pitcher", and two of Cleveland's starters, Luis Tiant and Sam McDowell, finished first and second in ERA in the American League.
Career statistics
In a twelve-year major league career, Sanford played in 388 games, accumulating a 137-101 win-loss record along with a 3.69 earned run average in 2,049 innings pitched. He accumulated 1,182 strikeouts and gave up only 840 earned runs. He also finished in the Top 10 in MVP Award voting twice in his career. He finished second in the league in wins twice, losing in 1957 to only Warren Spahn and in 1962 to Cy Young Award winner Don Drysdale.
Later life
After retiring from baseball, Sanford was a golf director at country clubs. Sanford died of a brain tumor at age 70 in Beckley, West Virginia.
