Milliken returned to Nebraska in 1988 where he accepted the position of executive assistant to the president of the University of Nebraska, and he was subsequently appointed Secretary to the Board of Regents and Vice President for External Affairs. In 1998, Milliken was appointed by then-president of the University of North Carolina, Molly Corbett Broad to lead university-wide strategy, institutional research, state and federal relations, public affairs, and economic development. In 2000, Milliken helped pass a statewide referendum for a $3.1 billion bond issue for university and community college facilities. Milliken was appointed president of the University of Nebraska in 2004. He worked to expand access and launched CollegeBound Nebraska, which provided free tuition to Nebraska Pell Grant recipients, University of Nebraska Online Worldwide, and Nebraska Innovation Campus, a public-private research and development park located on the former state fair grounds next to the University of Nebraska-Lincoln campus. He subsequently led a $1.8 billion capital campaign, funding new institutes for early childhood, global food and water sustainability and rural sustainability. Milliken also helped lead the Nebraska P-16 Initiative to improve primary education and increase college preparation. He expanded the University's global reach, establishing new programs, with universities, the private sector and government, in China, India, Brazil and Turkey. Milliken became Chancellor of the City University of New York in 2014, and held the position through 2018. During his time as Chancellor, there has been federal and state investigations of institutional corruption at the university. In November 2016, an interim report of an investigation conducted by the office of New York State Inspector General found "financial waste and abuse", citing shoddy oversight and mismanagement that created a system ripe for financial waste and abuse, and criticized Milliken and CUNY General Counsel Frederick Schaffer, among others, for failing to "effectively operate" the university system. During the year preceding Milliken's resignation, New York State GovernorAndrew Cuomo replaced CUNY Board of Trustees chairmen Benno C. Schmidt Jr. with a new chairmen Bill Thompson, and nearly all of the members of CUNY's board of trustees with a new politically prominent bloc, about whom Milliken said, "will have their own ideas about CUNY, and they should have the opportunity to help shape the leadership and agenda for the future." After state and federal investigation into financial irregularities in the CUNY system went public, top CUNY officials left their posts, beginning with the former president of the City College of New YorkLisa Staiano-Coico; CUNY Vice Chancellor of Legal Affairs and General Counsel Frederick P. Frederick P. Schaffer; CUNY Executive Vice Chancellor and Chief Operating Officer Allan H. Dobrin; CUNY Vice Chancellor for Research Gillian Small; and CUNY Senior Vice Chancellor of University Relations Jay Hershenson. Milliken is a member of the Council on Foreign Relations, Business Higher Education Forum, and on the executive committee of the Council on Competitiveness. He formerly served as a director on the board of the Association of Public and Land-Grant Universities, and led the Commission on Innovation, Competition and Economic Prosperity.
Personal life
Since 1989, Milliken has been married to Nana Graves Hilliard Smith, a graduate of Yale University, and New York University School of Law. They have three children.