Cardinal Barragán has expressed strong opposition to abortion, especially with regards to the RU-486 pill, which has abortive effects on the conceptus.
Cardinal Lozano Barragán was among the first to promote the canonization of Pope John Paul II after his death in April 2005, claiming that the 1990 recovery of a boy with terminal leukemia, whom the Pope blessed, is a miracle attributable to John Paul.
AIDS and contraception
In 2006 it was reported that Cardinal Lozano Barragán was preparing a report for Pope Benedict which might state that using condoms is the lesser of two evils when one of the people is infected with AIDS However, the story was later downplayed when the cardinal declared that he did not have the authority to give definitive doctrinal directives. Moreover, in 2009, Pope Benedict XVI argued that the spread of AIDS "cannot be overcome by the distribution of prophylactics: on the contrary, they increase it."
Euthanasia
Cardinal Lozano Barragán has publicly intervened in high-profile euthanasia cases, notably with Terri Schiavo and Eluana Englaro, which he unabashedly described as murders.
Homosexuals and transsexuals
In December 2009 a website published a statement by Cardinal Lozano Barragán in which he said that, while the Church regarded homosexuality as an insult to God, this did not justify discrimination against gay and transsexual people. The cardinal quoted Saint Paul'sLetter to the Romans as indicating that homosexuals and transsexuals will never enter the kingdom of heaven. He later clarified that this did not mean that no individual homosexual can be saved, since existence of grave fault requires not only grave matter but also full knowledge and consent, and since being homosexual is often due not to personal fault but to education and environment. Saying that people are not born homosexual, he attributed homosexuality to reasons such as education and failure to develop one's identity during adolescence. Holy See Press Office spokesman Fr Federico Lombardi, S.J. said the website should not be considered an authority on Catholic thinking "on complex and delicate issues such as homosexuality". For the teaching of the Catholic Church on the matter, Lombardi referred to , which states that, while "homosexual acts are intrinsically disordered", those who have homosexual tendencies "must be accepted with respect, compassion and sensitivity" and "every sign of unjust discrimination in their regard should be avoided".