After gaining registration as a nurse, Purdy moved to Southampton General Hospital, but was unhappy there and applied for a research post locally to work on tissue rejection, before transferring to Papworth Hospital in her home county where the first open-heart surgeries were pioneered in Britain. In 1968, she applied for and obtained a post with Robert Edwards at the Physiological Laboratory in Cambridge.
Work with Edwards and Steptoe
Steptoe became the Director of the Centre for Human Reproduction, Oldham in 1969. Using laparoscopy, he collected the ova from volunteering infertile women who saw his place as their last hope to achieve a pregnancy. Purdy began her work with the Steptoe and Edwards as a lab technician. She played a significant and increasingly vital role, to the extent that, when she took time off to care for her sick mother, work had to pause. During this time they had to endure criticism and hostility to their work. It was Purdy who first saw that fertilised egg, which was to become Louise Brown, was dividing to make new cells. The birth of Louise Brown in 1978 changed perceptions and to accommodate the increased demand and to train specialists, the team founded the Bourn Hall Clinic, Cambridgeshire in 1980. Purdy was a co-author on 26 papers with Steptoe and Edwards, and 370 IVF children were conceived during her career.
When it was decided that a plaque should be put up to record the achievement Edwards suggested that the plaque should be phrased "Human in vitro fertilisation followed by the world’s first successful pregnancy was performed at this hospital by Dr. Robert Edwards, Mr. Patrick Steptoe, Miss Jean Purdy and their supporting staff in November, 1977". Recognition for Purdy was ignored and the Oldham NHS Trust received a letter of complaint from Edwards in 1982. Bourn Hall erected a plaque in 2013 which again ignored Purdy's contribution. In a plenary lecture in 1998, celebrating the 20th anniversary of clinical IVF, Robert Edwards gave tribute to Jean Purdy, saying 'There were three original pioneers in IVF and not just two'. Professor Andrew Steptoe, son of Patrick Steptoe unveiled a plaque in 2015 that acknowledged the three people who were involved in developing IVF. In 2018, to mark the 40th anniversary of IVF, Bourn Hall unveiled a memorial to Jean Purdy, the "world's first IVF nurse and embryologist. Co-founder of Bourn Hall Clinic".