After a standout career playing at Noxubee County High School in Mississippi, Simmons was considered a five-star prospect and committed to Mississippi State over Alabama and Ole Miss. Simmons played in 12 games, starting three, as a true freshman in 2016. He had a breakout season in 2017 and was a consensus selection to the 2017 All-SEC football team. On December 20, 2018, Simmons declared for the 2019 NFL Draft. On February 12, 2019, Simmons tore his ACL while training for the draft.
College statistics
Professional career
Simmons was drafted by the Tennessee Titans with the 19th pick in the 2019 NFL Draft.
2019 season: Rookie year
On May 22, 2019, Simmons signed a four-year $12.66 million rookie contract with a team option for a fifth year with a $7.23 million signing bonus. He was placed on the reserve/non-football injury list to start the 2019 season while recovering from his torn ACL. On October 19, 2019, the Titans activated Simmons from the non-football injury list. He made his NFL debut the next day against the Los Angeles Chargers. In the game, Simmons recorded 4 tackles and sacked Philip Rivers once in the 23–20 win. The Titans finished with a 9-7 record, qualifying for the playoffs, with Simmons starting all seven games from weeks 8 to 15, recording 32 tackles, two sacks, and one pass deflection. In the playoffs, the Titans won upsets over the New England Patriots and the Baltimore Ravens before losing the AFC Championship game against eventual Super Bowl champions, Kansas City Chiefs, with Simmons playing in all three games. In the Divisional Round against the Ravens, Simmons recovered a fumble forced by teammate Jurrell Casey on Lamar Jackson during the 28–12 road victory.
NFL statistics
Regular season
Postseason
Personal life
In college, Simmons was a two-time member of the SEC Academic Honor Roll. Simmons' brother, Dylan Bradley, played football at Southern Miss and then spent time with the Minnesota Vikings while his uncle, Jason Hatcher, played 10 total seasons with the Dallas Cowboys and Washington Redskins. Away from football, Simmons enjoys fishing and spending time outdoors. He has a son named Jeffery Jr. and two sisters, Brooke and Ashley.