Colón was very creative as a child and had an early interest in music, science and art. Her grandfather, Eliseo Alvarado, was a well known musician in Orocovis, Puerto Rico. When she was 4 years old her brother was born with a rare disease called nonketotic hyperglycinemia. This and the flooding of their family home in San Juan made her parents move with her grandparents in Orocovis Puerto Rico for a few months. The sound of Colón's grandfather playing the cuatro left a mark in her heart and created a passion for sounds and melodies. In 2005, she graduated with honors from high school Colegio Bautista in Levittown, Puerto Rico and studied chemistry for three years at Universidad Interamericana de Puerto Rico in Cupey. In 2008, she changed her major to architecture, studying at the Polytechnic University of PR, but only for one year. As a model, Colón appeared in many editorials and fashion shows in Puerto Rico and is one of the most sought after models on the island.
On October 22, 2008, Colón competed in the Miss Puerto Rico Universe 2009 competition representing San Juan municipality. She was considered a strong contender and was predicted by many to win the pageant. However, she placed 1st runner-up to Mayra Matos of Cabo Rojo. She also won the award for "Most Beautiful Hair".
In early 2009, Colón decided to represent her hometown of Bayamón in the Miss World Puerto Rico 2009 pageant, held on July 23, 2009 in Puerto Rico. Prior to the final competition, Colón won the Top Model fast-track event on July 9, which automatically guaranteed her a spot as a semi-finalist. Ivonne Orsini, who won the title of Miss World Puerto Rico 2008, would eventually crown Colón as Miss World Puerto Rico 2009.
Through people in Miss World Puerto Rico, she met Elan Allende, son of Fernando Allende. On September 21, 2010 Colón and Allende secretly wed in Puerto Rico with only relatives present. The couple's daughter Maria Valentina was born on June 21, 2011. On April 20, 2012 the couple welcomed their second child, son Fernando Jose. Together they form the Latin pop music duo called Shambayah. Now both Elan and Jenny are cast members for the hit reality TV show on Bravo TV called Mexican Dynasties.