Yuh was born in 1972 in South Korea and immigrated to the United States with her parents and two sisters when she was 4 years old. She started sketching and drawing at a young age, while developing an interest with 80s action movies and anime. Her favorite filmmakers were James Cameron, Ridley Scott, and Katsuhiro Otomo. Yuh spent her childhood in Lakewood, California, where she enjoyed watching martial arts movies, playing with cars, and drawing. "I have been drawing since age 3 and making movies in my head for almost as long. In fact, drawing for me was a way to express those films when I had no other means of doing so," said Yuh. As a young girl, she would sit at the kitchen table for hours and watch her mother draw, copying her every stroke. As a kid, she would fancy stories with her sisters and was learning to draw to get down those stories. Yuh traces the lineage of her career to those formative family experiences. Interested in art, Yuh followed her sisters to California State University, Long Beach, where she received a Bachelor of Fine Arts in Illustration. There she got introduced to animation, "When I was in college years later, a veteran storyboard artist came to talk to my class. He showed us how he drew movies for a living. My mind exploded. And that led to a career in animation." Jennifer then followed her sisters into the animation industry, at first working as a cleanup artist at Jetlag Productions, where she worked on various direct-to-video features. Following a brief stint at Hanna-Barbera Productions on The Real Adventures of Jonny Quest for Cartoon Network, she was later hired as a storyboard artist on HBO's Todd McFarlane's Spawn series in 1997. In 1998, Yuh joined DreamWorks Animation as a storyboard artist, where she worked on ', ', and Madagascar. As a big fan of martial arts movies, she asked to work on the first Kung Fu Panda film, where she served as head of story and director of the opening hand-drawndream sequence. After the release of Kung Fu Panda, Jeffrey Katzenberg, DWA's CEO at the time, approached Yuh about directing Kung Fu Panda 2. Although she hadn't expressed interest in directing the sequel to the film, Producer Melissa Cobb stated that she should direct the second one due to her excellent work on the first, to which the rest of the crew supported the decision. The film proved a major critical and international box office success with a worldwide gross of $665.6 million, making it the highest-grossing film ever directed by a woman until director Jennifer Lee's Frozen two years later. She held the record for highest-grossing film by a solo female director until the release of Patty Jenkins' 2017 film Wonder Woman. She eventually became the first woman to be nominated for the Academy Award for Best Animated Feature Film and to win the Annie Award for Best Directing in a Feature Production. Yuh returned to co-direct Kung Fu Panda 3 alongside Alessandro Carloni, which was released in 2016. In July 2016, she was also added as one of the board of Governors by Academy of Motion Picture Arts and Sciences. In 2016, Yuh announced that would be making her live action directorial debut with an adaptation of Alexandra Bracken's The Darkest Minds for 20th Century Fox. Producer Shawn Levy praised Jennifer for her visual sensibility as well as her natural narrative qualities. She described herself as soft-spoken, contrary to what contemporary directors are often personified as; instead, she used storyboards to help pitch her ideas to Shawn Levy and 21 Laps. In June 2019, Yuh was hired as supervising director of the second season of the Netflix animated anthology series, Love, Death & Robots.
