Jerome Lettvin
Jerome Ysroael Lettvin, often known as Jerry Lettvin, was an American cognitive scientist, and Professor of Electrical and Bioengineering and Communications Physiology at the Massachusetts Institute of Technology. He is best known as the lead author of the paper, "What the Frog's Eye Tells the Frog's Brain", one of the most cited papers in the Science Citation Index. He wrote it along with Humberto Maturana, Warren McCulloch and Walter Pitts, and in the paper they gave special thanks and mention to Oliver Selfridge at MIT. Lettvin carried out neurophysiological studies in the spinal cord, made the first demonstration of "feature detectors" in the visual system, and studied information processing in the terminal branches of single axons. Around 1969, he originated the term "grandmother cell" to illustrate the logical inconsistency of the concept.
Lettvin was also the author of many published articles on subjects varying from neurology and physiology to philosophy and politics. Among his many activities at MIT, he served as one of the first directors of the Concourse Program, and, along with his wife Maggie, was a houseparent of the Bexley dorm.
Early life
Lettvin was born February 23, 1920 in Chicago, the eldest of four children of Solomon and Fanny Lettvin, Jewish immigrants from Ukraine. After training as a neurologist and psychiatrist at the University of Illinois, he practiced medicine during the Battle of the Bulge. After the war, he continued practicing neurology and researching nervous systems, partly at Boston City Hospital, and then at MIT with Walter Pitts and Warren McCulloch under Norbert Wiener.Scientific philosophy
Lettvin considered any experiment a failure from which the experimental animal does not recover to a comfortable happy life. He was one of the very few neurophysiologists who successfully recorded pulses from unmyelinated vertebrate axons. His main approach to scientific observation seems to have been reductio ad absurdum, finding the least observation that contradicts a key assumption in the proposed theory. This led to some unusual experiments. In the paper "What the Frog's Eye Tells the Frog's Brain", he took a major risk by proposing feature detectors in the retina. When he presented this paper at a conference, he was laughed off the stage by his peers, yet for the next ten years it was the single most cited scientific paper. For Lettvin, a corollary to finding contradictions was taking risks: the bigger the risk, the likelier a new finding. Robert Provine quotes him as asking, "If it does not change everything, why waste your time doing the study?"Lettvin made a careful study of the work of Leibniz, discovering that he had constructed a mechanical computer in the late 17th century.
Lettvin is also known for his friendship with, and encouragement of the cognitive scientist and logician Walter Pitts, a polymath who first showed the relationship between the philosophy of Leibniz and universal computing in a seminal paper Pitts co-authored with Warren McCulloch.
Lettvin continued to research the properties of nervous systems throughout his life, culminating in his study of ion dynamics in axon cytoskeleton.
in Building 20 at MIT in 1952.
Politics
Lettvin was a firm advocate of individual rights and heterogeneous society. His father nurtured these views with ideas from Kropotkin's book . Lettvin became an expert witness in trials in both the United States and in Israel, always on behalf of individual rights.During the anti-war demonstrations of the 1960s, Lettvin helped to negotiate agreements between police and protesters, and in 1968 he took part in the student takeover of the MIT Student Center in support of an AWOL soldier. He deplored the making of laws based on false science and false statistics, and the distortion of observations for political or economic advantage.
When the American Academy of Arts and Sciences withdrew its award of the annual Emerson-Thoreau medal from Ezra Pound because of his vocal support for Italian Fascism, Lettvin resigned from the Academy and wrote in his resignation letter: "It is not art that concerns you but politics, not taste but special interest, not excellence but propriety."
Debating
On May 3, 1967, in the Kresge Auditorium at MIT, Lettvin debated with Timothy Leary about the merits and dangers of LSD. Leary took the position that LSD is a beneficial tool in exploring consciousness. Lettvin took the position that LSD is a dangerous molecule that should not be used.Lettvin was a regular invitee at the Ig Nobel Prize ceremony as "the world's smartest man," and debated extemporaneously against groups of people on their own subjects of expertise.
Personal life
Lettvin married his wife, Maggie in 1947. They had three children: David, Ruth, and Jonathan.Death
Lettvin died on April 23, 2011, in Hingham, Massachusetts at the age of 91.Published papers
- Year Title, Publication, Issue; Contributing Authors
- 1943 A Mathematical Theory of the Affective Psychoses, Bulletin of Mathematical Biophysics, Vol. 5;
- 1948 Somatic Functions of the Central Nervous System, Annual Review of Physiology Vol. 10;
- 1948 The Path of Suppression in the Spinal Grey Matter, Federation Proceedings, Vol. 7, No. 1, March;
- 1950 An Electrical Hypothesis of Central Inhibition and Facilitation, Proceedings of the Association for Research in Nervous and Mental Diseases, Vol. 30, December;
- 1950 Positivity in Ventral Horn During Bulbar Reticular Inhibition of Motoneurons Federation Proceedings, Vol. 9, No. 1, March;
- 1951 Changes Produced in the Central Nervous System by Ultrasound, Science, Vol. 114, No. 2974;
- 1952 Sources and Sinks of Current in the Spinal Cord, Federation Proceedings, Vol. 11, No. 1, March;
- 1953 Comparaison entre les machines à calculer et le cerveau, Les machines à calculer et la pensée humaine, Vo.l. 37, pp. 425–443;
- 1953 On Microelectrodes for Plotting Currents in Nervous Tissue, Proceedings of the Physiological Society, Vol. 122;
- 1954 Maps Derived by Bipolar Microelectrode Stimulation Within the Spinal Cord, Federation Proceedings, Vol. 13, March;
- 1955 Physiology of a Primary Chemoreceptor Unit, Science, Vol. 122, No. 3166, September;
- 1955 Reflex Inhibition by Dorsal Root Interaction, Journal of Neurophysiology', vol.18;
- 1955 Effects of Strychnine, with Special Reference to Spinal Afferent Fibers, Epilepsia, Series III, Vol. 4;
- 1955 The Terminal Arborisation of the Cat's Pyramidal Tract Determined by a New Technique, The Yale Journal of Biology and Medicine, Vol. 28, Nos. 3-4, Dec.-Feb.;
- 1956 Excitability Changes in Anatomical Components of the Monosynaptic Arc Following Tetanic Stimulation, Federation Proceedings, Vol. 15, No. 1, March;
- 1956 Limits on Nerve Impulse Transmission, IRE Convention Record, National, Part 4, March 19–20;
- 1956 Central Effects of Strychnine on Spinal Afferent Fibers, A.M.A. Archives of Neurology and Psychiatry, Vol. 75: 323-324;
- 1957 Membrane Currents in Clamped Vertebrate Nerve, Nature, Vol. 180, pp. 1290–1291, Dec. 7;
- 1956/1957 Footnotes on a Headstage, IRE Transactions on Medical Electronics;
- 1956 Evidence that Cut Optic Nerve Fibers in a Frog Regenerate to their Proper Places in the Tectum, Science, Vol. 130, No. 3390, December;
- 1959 How Seen Movement Appears in the Frog's Optic Nerve, Federation Proceedings Vol. 18, No. 1, March;
- 1959 , Proceedings of the IRE, Vol. 47, No. 11, November;
- 1959 Comments on Microelectrodes, Proceedings of the IRE, Vol. 47, No. 11, November;
- 1959 Number of Fibers in the Optic Nerve and the Number of Ganglion Cells in the Retina of Anurans, Nature, Vol. 183, pp. 1406–1407, May 16;
- 1959 Bridge for Measuring the Impedance of Metal Microelectrodes, The Review of Scientific Instruments, Vol. 30, No. 4, April;
- 1960 Anatomy and Physiology of Vision in the Frog, The Journal of General Physiology, Vol. 43, No. 6, Supplement pp. 129–175;
- 1961 Two Remarks on the Visual System of the Frog, Research Laboratory of Electronics, MIT, Vol. 38;
- 1962 , The Fat Abbot, Fall/Winter 1962
- 1963 Odor Specificities of the Frog's Olfactory Receptors, Proceedings of the First International Symposium on Olfaction and Taste ;
- 1964 A Theory of Passive Ion Flux through Axon Membranes, Nature, Vol. 202, No. 4939, pp. 1338–1339, June;
- 1964 Microelectrodes Research Laboratory of Electronics, MIT Encyclopedia of Electrochemistry,, pp. 822–826;
- 1964 Receptor Model of the Frog's Nose, NEREM Record;
- 1964 Caesium Ions Do Not Pass the Membrane of the Giant Axon, Proceedings of the National Academy of Sciences, Vol. 52, No. 5, pp. 1177–1183;
- 1964? Lanthanum Simulates High Calcium and Reduces Conductance Changes in Nerve Membranes, XXIII International Congress of Physiological Sciences ;
- 1964 Passive Transport of Ions Across Nerve membranes, Minutes of the APS-NES 1964 Spring Meeting of the New England Section, 4 April;
- 1964 Experiments in Perception, Tech Engineering News, November;
- 1965 Chemical Transmission in the Nose of the Frog, Journal of Physiology, Vol. 181, pp. 525–559;
- 1965 Octopus Optic Responses, Experimental Neurology, Vol. 12, No. 3, July;
- 1965 Glass-Coated Tungsten Microelectrodes, Science, Vol. 148, No.3676, pp. 1462–1464;
- 1965 Speculations on Smell, Cold Spring Harbor Symposia on Quantitative Biology, Vol. 30;
- 1965 General Discussion: Early Receptor Potential, Cold Spring Harbor Symposia on Quantitative Biology, vol. 30;
- 1966 Ionic Conductance Changes in Lobster Axon Membrane When Lanthanum is Substituted for Calcium, Journal of General Physiology, Vol. 50, Number 2, November;
- 1966 Alkali Cation Selectivity of a Squid Axon Membrane, N.Y. Academy of Sciences, vol. 137, pp. 818–829;
- 1966 A Demonstration of Ion-Exchange Phenomena in Phospholipid Mono-Molecular Films, Nature, Vol. 209, No. 5026, pp. 886–887, February;
- 1967 You Can't Even Step in the Same River Once, Journal of the American Museum of Natural History , Vol. 76, No. 8, October;
- 1967
- 1968 A Code in the Nose, Cybernetic Problems in Bionics ;
- 1968 Pure Renaissance, Natural History, June–July, p. 62
- 1969 The Annotated Octopus, Natural History, Vol. 78, No. 9, p. 10;
- 1970 Multiple Meaning in Single Visual Units, Brain, Behavior and Evolution, vol.3, pp. 72–101;
- 1970 The Rise and Fall of Progress, Natural History, Vol. 79, No. 3, pp. 80–82, March
- 1972 Scratched and Chiseled Marks of Man, Natural History
- 1974 The CLOOGE: A Simple Device for Interspike Interval Analysis, Proceedings of the Physiological Society, vol. 239, pp. 63–66, February;
- 1976 A Physical Model for the Passage of Ions through an Ion-Specific Channel - I. The Sodium-Like Channel, Mathematical Biosciences, vol.32, pp. 37–50;
- 1976 Probability of Conduction Deficit as Related to Fiber Length in Random-Distribution Models of Peripheral Neuropathies, Journal of the Neurological Sciences, Vol. 29, pp. 39–53;
- 1976 The Use of Myth, Technology Review, Vol. 78, pp. 52–57
- 1976 On Seeing Sidelong, The Sciences, Vol. 16, No. 4, July/August
- 1977 The Gorgon's Eye, Technology Review, Vol. 80, pp. 74–83
- 1977 Freedoms and Constraints in Color Vision, Brain Theory Newsletter, Vol. 3, No. 2, December;
- 1978 Aftereffects of Activity in Peripheral Axons as a Clue to Nervous Coding, Physiology and Pathobiology of Axons, edited by Waxman ;
- 1978 Relation of the E-Wave to Ganglion Cell Activity and Rod Responses in the Frog, Vision Research, Vol. 18, pp. 1181–1188;
- 1980 Anatomy and Physiology of a Binocular System in the Frog Rana pipiens, Brain Research Vol. 192, pp. 313–325;
- 1983 Processing of Polarized Light by Squid Photoreceptors, Nature, Vol. 304, pp. 534–536;
- 1986 The Colors of Things, Scientific American'', Vol.255.3, pp. 84–91; September
- 1995