DuBose accepted an athletic scholarship to attend the University of Florida in Gainesville, Florida, where he played fullback for coach Doug Dickey's Florida Gators football team from 1972 to 1975. Dickey described him as a "picture perfect fullback," able to run over people like a fullback but also able to run like a halfback in the open field. Memorably, DuBose ran for 180 yards against the Vanderbilt Commodores, including an eighty-yard touchdown run on the first play from scrimmage, and rushed for 204 yards versus the Florida State Seminoles as a senior. Averaging nearly seven yards per carry, he led the Gators to a 9–2 record, the first time the Gators had achieved nine regular-season wins. DuBose's 2,159 career rushing yards are, as of 2009, the tenth-best in Gators team history; his senior-year effort of 1,307 yards remains the Gators' third-best season total. As a senior team captain in 1975, he rushed for 1,402 yards and six touchdowns on 209 carries, and was recognized as a first-team All-Southeastern Conference selection, the SEC Player of the Year, and a second-team All-American; he also finished sixth in the Heisman Trophy balloting. DuBose was the recipient of the Gators' Fergie Ferguson Award recognizing the "senior football player who displayed outstanding leadership, character and courage." He graduated from Florida with a bachelor's degree in public relations in 1980, and was inducted into the University of Florida Athletic Hall of Fame as a "Gator Great" in 1987.
Professional career
DuBose was selected by the expansion Tampa Bay Buccaneers in the second round of the 1976 NFL Draft, following the Buccaneers' first-round pick, Leroy Selmon, and became part of the inaugural Buccaneers line-up. Hobbled by an injured ankle in his rookie season in, he had trouble learning the Bucs system. Playing with a year's experience behind an improved line, he was the Bucs' most consistent runner in the preseason, earning the praise of Buccaneers offensive coordinatorJoe Gibbs. In, he became the Buccaneers' first-ever running back to gain 100 yards in a game. Unfortunately, only four plays after achieving this milestone, he tore knee ligaments while tackling New York Giants linebacker Harry Carson after an interception, an injury that benched him for the entire season. He never regained his pre-injury form, and was traded to the Miami Dolphins in, along with a second-round draft pick for running back Gary Davis and cornerback Norris Thomas. Miami coach Don Shula cut DuBose from the squad, feeling that he would, at 205 pounds, be too small to replace Larry Csonka. In his three-season NFL career, DuBose appeared in thirty-three games, started fifteen of them, and rushed for 704 yards and four touchdowns on 184 attempts. He also compiled seventeen receptions for 118 yards.
Life after football
DuBose is married, and he and his wife have a son and a daughter. DuBose and his wife worked in education. DuBose retired in 2018.
