John Fincham


John Robert Stanley Fincham FRS FRSE was a noted British geneticist who made important contributions to biochemical genetics and microbial genetics.

Education and Personal life

Fincham was educated at Peterhouse, Cambridge, where he read Natural Sciences. He earned his PhD in the Botany School at Cambridge and then did a year's postgraduate research at the California Institute of Technology with Sterling Emerson.

Career and Research

Fincham laboratory was among the first to demonstrate "intragenic complementation" through finding "pseudowild" progeny from am1 × am2 crosses. He obtained the first direct evidence for the "one gene-one enzyme" hypothesis, using mutants of Neurospora crassa deficient in a specific enzyme called glutamate dehydrogenase.
Fincham was appointed first as lecturer in botany and then as reader at University of Leicester. A year as an associate professor in the Massachusetts Institute of Technology preceded his appointment as head of the Genetics Division of the John Innes Centre in 1961. Fincham's appointment at the JIC is an acknowledgement that much really progressive work in biology is now done with microorganisms and is a strategic move by K.S. Dodds to give JIC leadership in the field. During his time at the John Innes Centre, his treatise with Peter Day, the first edition of Fungal Genetics was released. The book gathered existing knowledge of basic biology, recombination, tetrad analysis, mating systems, and extranuclear inheritance together with a single chapter on biochemical genetics, which provided a common background to a growing community of scientists.
He remained at the John Innes until 1966, when he was appointed as professor and head of the newly established Department of Genetics at University of Leeds. In 1976, John was appointed to the Buchanan Chair of Genetics in Edinburgh and was head of the Department of Genetics until 1984.
Fincham was the Arthur Balfour Professor of Genetics at the University of Cambridge between 1984 and 1991. He was elected a Fellow of the Royal Society in 1969 and a Fellow of the Royal Society of Edinburgh in 1978. He was president of the Genetics society from 1978 to 1981. In 1977 he was
awarded the Emil Christian Hansen Medal for his contribution to research into fungi.