Osborne was born on 10 June 1953 in Manchester, England. She began studying law until she felt "the hand of Heaven" and decided to study for the ministry. She attended Manchester University, where she graduated in sociology, after which she worked as a lay person in parish ministry at St Aldate's Church, Oxford. She then moved to the administrative staff of the Universities and Colleges Christian Fellowship, where she directed the week-long 'Vocation 78' conference. This event, attended by 1400 evangelical students from the UK and overseas, aimed to help professionals develop "thorough-going Christian minds" so as to allow their faith to influence them in their work. From UCCF she moved to Wycliffe Hall, Oxford to undertake ordination training, following a sense of calling to parish ministry: "Women should be prepared to put aside their natural reticence take on full participation in the leadership in the church", however she state that "the whole structure of ministry needs to be changed so that we do not put anybody in an isolated position at the top as happens at present. It should be a team". She was the first woman to take up a place at the previously all-male college. She also undertook training at St John's College, Nottingham.
Ordained ministry
In 1980, she became a deaconess at St Martin in the Bull Ring, Birmingham. She has also served at St Aldate's Church, Oxford, and in the Old Ford parishes in London. In the 1980s she was a regular speaker at the GreenbeltChristian music festival. She was made one of the first woman deacons in the Church of England in 1987. Osborne was ordained to the priesthood in 1994, one of the first women to be ordained in England. There was much discussion at the previous year's Church General Synod as to whether or not to ordain female priests. The Times attributed Osborne's speech at the synod "for swinging the General Synod vote in favour of female priests". She moved in the following year to Salisbury, where she served as Canon Treasurer until her appointment as Dean. She was Dean of Salisbury from 1 May 2004 until July 2017. She was the first woman to serve as a Dean at Salisbury Cathedral and the first at any of England's medieval cathedrals. She had served as acting dean since the retirement of her predecessor, Derek Watson, in 2002. She is interested in interfaith dialogue and currently sits on the Board of World Religious Leaders for the Elijah Interfaith Institute.
Episcopal ministry
In 2014, after the vote to allow for the consecration of women as bishops, there was speculation that Osborne could become the first female bishop in the Church of England. On 27 April 2017, it was announced that Osborne would be the next Bishop of Llandaff in the Church in Wales. Her election was confirmed at a Sacred Synod meeting on 14 July 2017, whereby she legally took up her new post. She was consecrated a bishop on 15 July 2017 by John Davies, Bishop of Swansea and Brecon, during a service at Brecon Cathedral. She was installed as the 72nd Bishop of Llandaff during a service at Llandaff Cathedral on 22 July.
