Jung first attracted attention when she made her acting debut in 2010 with a supporting role in the television seriesBad Guy. This led to a leading role in her next project Playful Kiss, the Korean adaptation of the popular mangaItazura na Kiss. Though it received low ratings in Korea, the romantic comedy was popular overseas, further raising Jung's profile. Jung then took a short break in 2011 to concentrate on her studies at the Korea National University of Arts. In 2012 she returned to the small screen as part of the ensemble cast of the sitcom Standby. Later that year, she played a more mature role opposite Sung Joon in the cable series Can We Get Married?. Jung left her talent agency Bloom Entertainment in 2013, and joined SM Culture & Contents. She then appeared in Came to Me and Became a Star, on single-episode anthology Drama Special. In 2014, Jung played a self-centered heiress who falls for the protagonist in Big Man. This was followed in 2015 by a supporting role in coming-of-age filmTwenty, and leading roles in horror-romance film Alice: Boy from Wonderland and disaster/medical drama D-Day. In December 2016, she starred as the female lead in The Sound of Your Heart opposite Lee Kwang-soo. The web drama was a success in China and gained more than 100 million views on Sohu. In 2017, Jung starred in KBS' weekend family dramaMy Father is Strange. The same year, she starred in the body-swap comedy Daddy You, Daughter Me opposite veteran actor Yoon Je-moon. Jung left SM Culture & Contents in June 2017 and signed with new management agency Jellyfish Entertainment. In August, Jung confirmed her appearance in tvN's romantic comedy seriesBecause This Is My First Life alongside Lee Min-ki. In 2018, Jung was cast in The Smile Has Left Your Eyes adaptation of the 2002 Japanese television seriesSora Kara Furu Ichioku no Hoshi. The same year she was cast in the historical comedy flick Gibang Bachelor. Jung left Jellyfish Entertainment in August 2019 and signed with another management company Blossom Entertainment. In 2020, Jung is set to star in the medical dramaSoul Mechanic.