KCNQ channels


KCQN genes encode family members of the Kv7 potassium channel family. These include Kv7.1 - KvLQT1, Kv7.2, Kv7.3, Kv7.4, and Kv7.5. Four of these are expressed in the nervous system. They constitute a group of low-threshold voltage-gated K+ channels originally termed the ‘M-channel’. The M-channel name comes from the classically described mechanism wherein the activation of the muscarinic acetylcholine receptor deactivated this channel.