KDM6B


Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B gene.

Regulation during differentation

KDM6B was found to be expressional increased during cardiac and endothelial differentation of murine embryonic stem cells.

Small molecule inhibition

A small molecule inhibition has been developed to inhibit jumonji domain of KDM6 histone demethylase family to modulate proinflammatory response in macrophage.