Karl von Pfeufer Karl Sebastian von Pfeufer was a German physician who was a native of Bamberg . He studied at Erlangen and Würzburg , and afterwards served as an assistant to Johann Lukas Schönlein . In 1840 he became a professor and director at the medical clinic in Zurich , and from 1844 worked at the university clinic in Heidelberg . In 1852 he was named clinical professor in the second medical division at the general hospital in Munich . Some of his better known students and assistants were Friedrich Albert von Zenker , Adolf Kussmaul , Theodor von Dusch and Otto Leichtenstern . Karl Pfeufer is remembered for his collaboration with anatomist Friedrich Gustav Jacob Henle , an association that began in the early 1840s at Zurich. The two doctors are credited as forerunners of German scientific medicine , and were pioneers in their attempts to create a synthesis between laboratory and clinic. In 1844 they founded a journal on "rational medicine" called Zeitschrift für rationelle Medizin , which was to become one of the more important medical journals in the German language . Pfeufer would maintain written correspondence with Henle until his death in 1869. Another publication by Pfeufer was an 1837 treatise on the cholera epidemic at Mittenwald , titled Bericht über die Cholera-Epidemie in Mittenwald .Works about Karl von Pfeufer Der Briefwechsel zwischen Jakob Henle und Karl Pfeufer, 1843-1890 , edited and revised by Hermann Hoepke. Wiesbaden: Steiner, 1970 - The correspondence between Jakob Henle and Karl Pfeufer 1843–1869. in Munich
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