The Tennessee Titans selected Bullock in the first round of the 2000 NFL Draft. Bullock was the fifth linebacker drafted in 2000 and was one of four Pro Bowl linebackers selected in the first round of the 2000 NFL Draft. The first round also included Pro Bowl linebackers LaVar Arrington, Brian Urlacher, and Julian Peterson. On July 1, 2000, the Tennessee Titans signed Bulluck to a four-year, $5.56 million contract that includes a signing bonus of $1.92 million. After spending his first two seasons as a backup and special teamer, he became a starter in 2002. After becoming a starter he made a Pro Bowl in 2003 and has led the Titans in tackles five times. In 2004, he led the NFL in tackles with 152. In 2007, he recorded a Titans-record five interceptions for a linebacker.
New York Giants
On July 24, 2010, after a private workout with the team, he signed a one-year, $2.5 million contract with the Giants. He became an unrestricted free agent following the season.
Retirement
Bulluck did not play in the 2011 season after no teams signed him. After having the year off, he announced his retirement on January 25, 2012. On August 3, 2012, Bulluck formally retired from the National Football League with the team who drafted him, the Tennessee Titans. He became the first player in Titans franchise history to formally retire from their organization. Bulluck joined the Titans broadcast team in Summer 2013. On August 25, 2013, Bulluck was arrested in Nashville, Tennessee for allegedly robbing a taxi driver, although the claims by the taxi driver are disputed.. On September 13, 2013, charges were dropped.
In 2019 Bulluck partnered with the founders of the then 10-year-old conference series and sports media outlet "Blogs With Balls" to rebrand and relaunch under the umbrella "The Outside Game." Bulluck said in an announcement "The Outside Game was built to provide avenues that amplify conversation among athletes, creators, media, business, and marketers in an unfiltered and unbiased manner, just as BWB has for the past decade. The Outside Game gives athletes and contributors a real opportunity to address issues not exclusive to sport, and with a genuine voice and point of view rather than through the lens of corporate PR avenues." The first event under the rebrand was held September 5, 2019 at SubCulture in New York City and featured conversations with athletes PacMan Jones, Robin Lehner, Joanna Lohman, Alex Cavallini, and Jonathan Casillas, and media figures such as Greg Mescall, Erin Ashley Simon, Jeff Eisenband, Bleacher Report's Ben Osborne, and more. In addition to the events, Bulluck co-hosts The Outside Game Podcast which is a mix of conversation and interviews with individuals from across sports and culture.