On 4 December 2013, Keno was released by Águia as the club was immerse in a financial crisis. Twelve days later, he was announced at Paraná. Keno made his debut for the club on 26 January 2014, coming on as a second-half substitute in a 0–2 Campeonato Paranaense away loss against rivals Coritiba. His first goal came on 5 March, the second in a 2–1 win at Toledo Colônia Work. Keno made his professional debut on 2 May 2014, starting in a 1–1 away draw against Santa Cruz for the Série B championship. He appeared in three further matches for the club, all as a starter, before leaving due to unpaid wages.
Santa Cruz
On 14 June 2014, Keno signed for fellow second division club Santa Cruz, until the end of the year. He made his debut for the club 15 July, playing 21 minutes in a 1–4 away loss against Vasco da Gama. Keno scored his first professional goal on 9 August 2014, netting the first in a 3–0 home success over fierce rivals Náutico. He finished the campaign with three goals in 25 appearances for Santinha, as his side finished ninth.
On 22 June 2015 Keno returned to his home country, signing for Ponte Preta. He made his debut for the club – and in the Série A – on 11 July, replacing Felipe Azevedo in a 0–2 home loss against Atlético Mineiro. Keno made 12 league appearances for Ponte during his spell, all from the bench. His only goal for the club came on 22 July 2015, in a 2–1 Copa do Brasil home win against Coritiba; he was also sent off during the match.
Santa Cruz return
On 30 December 2015, Keno returned to his former club Santa Cruz. He made his second debut for the club the following 11 February in a 4–2 home win against América-PE, replacing Wallyson and receiving a straight red card after only three minutes on the field. Keno helped the club to achieve both Campeonato Pernambucano and Copa do Nordeste titles during the season, netting five goals in the latter competition. He scored his first goal in the main category of Brazilian football on 15 May 2016, netting the last in a 4–1 home routing of Vitória; it was also Santa's first game in the top tier after nearly ten years. On 18 September 2016, Keno scored a brace in a 2–3 away loss against Santos. The following weekend, he added another in a 1–3 loss at Figueirense, taking his tally up to eight goals.
At the end of 2016 Palmeiras announced the signing of Keno, confirming that he will join the club in January 2017. In 40 appearances he scored 9 goals. He was often called a pass and goal machine.
On 25 June 2018, it was announced that Keno had agreed to transfer to Egyptian side Pyramids for a fee US$10 million. Keno became the most expensive transfer of Egyptian football, and one of the few Brazilians playing in Pyramids
Al Jazira Club
On 7 July 2019, Al-Jazira has signed Keno on a one season loan.
Atlético Mineiro
In June 18 2020, Atlético Mineiro announced the signing of Keno on a three-year contract, with the option of a one-year extension.