Hudson attended McKeesport Area High School in Pennsylvania where he played safety and running back. He was recruited by several top programs as a two-way player. At the time of his January 27, 2016 commitment to Michigan he was the number one rated football prospect in the Pennsylvania statewide class of 2016 according to Scout.com and had offers from Pittsburgh, UCLA, and Penn State.
College career
Hudson made his debut on September 3, 2016 against Hawaii. In the 2016 campaign, Khaleke made an appearance in all 13 games primarily on special teams. Khaleke only appeared in 2 games as a Safety, and was the Special TeamsPlayer of the Game after a home win against Illinois. On November 4, 2017, he set the school single-game record with eight tackles for loss against Minnesota in the Little Brown Jugrivalry game, earning Big Ten Conference Co-Defensive Player of the week. Hudson was recognized as the FWAA/Bronko Nagurski National Defensive Player of the Week for the effort, which tied an NCAA single-game record and set a Big Ten Conference tackle for loss record. Following the 2017 season, Hudson, who was second in the conference in tackles for loss for the season, earned third-team All-Big Ten recognition from the coaches. Prior to his junior season in 2018, Hudson was named to preseason watch lists for the Lott Trophy and Bronko Nagurski Trophy. He was named preseason first-team all-Big Ten by Athlon Sports. Hudson appeared in all 13 games for the Wolverines but assumed a lesser role in the defense than his sophomore season. He finished with three tackles for loss and 39 total tackles on the year, and was named an honorable mention all-conference selection by both media and coaches. As a senior, Hudson was named to the preseason watchlist for the Butkus Award. During the 2019 season, Hudson was Michigan's leading tackler with a career-best 97 stops, including 3.5 for loss with two sacks. He added three pass breakups, three quarterback hurries, and a blocked kick. Following the season, Hudson was named to second-team 2019 All-Big Ten.
Professional career
Hudson was selected by the Washington Football Team in the fifth round, 162nd overall, of the 2020 NFL Draft. The Redskins had acquired the 162nd pick when they traded cornerback Quinton Dunbar to the Seattle Seahawks prior to the draft. He signed his four-year rookie contract with the team on July 23, 2020.
