Douglass-Ishizaka started playing the piano at age four, was a member of the Ishizaka Trio for 16 years with her brothers and graduated from Hochschule für Musik Köln. As a solo pianist, she has performed concerts throughout Europe, North America and Japan, as well as appearing with the Beethoven Orchester Bonn, the Klassische Philharmonie and the Jackson Symphony Orchestra. In 1998 Ishizaka was the winner of the Deutscher Musikwettbewerb, along with her brothers Kiyondo Ishizaka and Danjulo Ishizaka. Ishizaka is part of the Open Goldberg Variations, a Kickstarter-funded, and Bösendorfer-sponsored team that recorded Johann Sebastian Bach's Goldberg Variations and released the score and recordings into the public domain in May, 2012. In November 2013 Ishizaka and Open Goldberg Project completed another to fund the recording Book I of Bach's Well-Tempered Clavier. The new recording was . Donald Rosenberg, writing for Gramophone Magazine, writes that "She scales her Bach to the rhythmic, structural and sonic needs of the music, without touching the sustaining pedal." James Oestreich, reviewing for The New York Times, reported that Ishizaka is a "gifted and obviously devoted Bachian" and that she "performed the 24 preludes and fugues of Book 1 from memory and without major flaw". In April 2015, Ishizaka began another Kickstarter-funded project to record Chopin's 24 préludes on an 1842 Pleyel piano. The recordings were released under a Creative Commons license. Ishizaka made her debut as a composer on March 19, 2016, with her performance of Bach's The Art of the Fugue featuring her own completion of the final fugue. In 2017, she then recorded The Art of the Fugue, including her completion, and released it under a Creative Commons license, available for download in audiophile quality from her website. On October 1, 2019 Ishizaka released her album New Me! on her own website on the platform Bandcamp.
Weightlifting
Ishizaka explained in an interview that she began weightlifting after a convicted bank robber encouraged her to work out with free weights instead of relying on exercise machines and similar devices: Her weight training led to a change in her pianistic technique: She trains with 265lb of weights after practicing piano to maintain her piano performance level.
Powerlifting
Ishizaka was placed 3rd in the weight category < 82 kg in the 2005 German championships in powerlifting and in 2006 she placed 2nd in the disciplines of bench press, squat and deadlift.
Olympic weightlifting
Ishizaka won three medals at the 2008 German championships in olympic weightlifting. In the spring of 2008 she was placed 5th in the ELEIKO Women's Grand Prix in Niederöblarn, Austria in the 63 kg class.
