Léopold Nègre
Léopold Nègre was a French physician and biologist born in Montpellier.
He studied natural sciences at the University of Montpellier, followed by courses in microbiology at the Pasteur Institute in Paris. From 1907 to 1910 he served as préparateur at the laboratory of microbiology courses headed by Amédée Borrel. In 1910 he obtained his doctorate of medicine. Following an internship at the Pasteur Institute in Lille, he was appointed laboratory chief at the Pasteur Institute in Algiers. In 1918 he received his doctorate of natural sciences.
In 1919 he was assigned to the laboratory of tuberculosis headed by Albert Calmette at the Pasteur Institute in Paris. Here he took part in research of Bacillus Calmette-Guérin. With microbiologist Alfred Boquet he developed antigene méthylique for treatment of tuberculosis.
In 1931 Nègre became chair at the Institut Pasteur, and in 1944 was named vice president of the Société de biologie. He was also president of the Société française de la tuberculose and a member of the Académie de Médecine.Selected writings
- Infections à bacille pseudo-dysentériques en Algérie 1916
- Bacilles paradysentériques isolés en Algérie 1917
- Résultats des vaccinations triples antityphoïdiques et antiparatyphoïdiques dans les troupes d'Alger 1917
- Lymphangite epizootique des solipèdes : contribution a l'ètude des mycoses with Alfred Boquet; 1920
- Antigénothérapie de la tuberculose par les extraits méthyliques de bacilles de Koch with Alfred Boquet; 1927
- Le traitement de la tuberculose par l'antigène méthylique with Alfred Boquet; 1932
- Albert Calmette, sa vie, son oeuvre scientifique 1939
- Vaccination par le BCG par scarifications cutanées with J. Breley; 1942
- Prévention et traitement spécifiques de la tuberculose par le BCG et par l'antigène méthylique 1956
