Simoneau was born in Saint-Flavien, Quebec, and started his vocal studies in Quebec City at Levis College and Université Laval. While studying in Montreal with Salvator Issaurel, he made his professional debut with Les Variétés Lyriques in Montréal in 1941. He then left for New York City for complementary studies with Paul Althouse. In 1946 he appeared at the New York City Center as Lionel in Martha. That same year he married French-Canadian sopranoPierrette Alarie. Together they left for France. Simoneau made his debut in 1949 at the Opéra-Comique of Paris as Vincent in Gounod's opera Mireille and at the Paris Opera as Tamino in Die Zauberflöte. He made his debut at the Aix-en-Provence Festival in 1950 singing Ottavio in Don Giovanni and Ferrando in Così fan tutte. The following year, 1951, he made his debut at the Glyndebourne Festival as Idamante in Idomeneo. His performances at these two festivals quickly established him as the outstanding Mozartian tenor of his time. He was invited to sing at the Salzburg Festival and the Edinburgh Festival, at the Vienna State Opera and at La Scala in Milan, while pursuing his career in France, in roles such as Nadir in Les pêcheurs de perles, Gérald in Lakmé. He took part in the revival of opera such as Rameau's Les Indes galantes and Orphée in the French version for tenor of Gluck's Orfeo ed Euridice. In France he was frequently singing opposite his wife, who was a light lyric coloratura soprano excelling in the same repertoire as her husband. In the 1950s he made several famous recordings, including one of the Mozart Requiem with Bruno Walter conducting. He also participated in two celebrated recordings with Philips Records, Georges Bizet'sLes pêcheurs de perles conducted by Jean Fournet, and Christoph Willibald Gluck's Orphée et Euridyce conducted by Hans Rosbaud, in which he gave what some critics feel are the definitive performances of the roles of Nadir and Orphée. Simoneau also sang the role of Belmonte in Sir Thomas Beecham's recording of Mozart's The Abduction from the Seraglio, and the role of Ferrando in Mozart's Così fan tutte opposite Elisabeth Schwarzkopf, Nan Merriman, Rolando Panerai, Lisa Otto, Sesto Bruscantini, conducted by Herbert von Karajan, both considered classics. He also sang in Charles Munch's critically acclaimed 1959 recording of the Berlioz Requiem. Simoneau made his debut at the Lyric Opera of Chicago in 1954, he sang there until 1961, notably in La traviata opposite Maria Callas. His only Metropolitan Opera appearances were five performances of Don Ottavio during the 1963-64 season. Simoneau's final appearance was in Handel's Messiah in Montréal on November 24, 1970. He was made an Officer of the Order of Canada in 1971, he was promoted to Companion in 1995. Simoneau was also made a Knight of the National Order of Quebec in 1997. After retiring, Simoneau and his wife became active as teachers, notably at the Banff Centre. They also founded the Canada Piccola Opera in Victoria, British Columbia, in 1982. He and his wife had two daughters, Isabelle and Chantal. Léopold Simoneau died at his home on August 24, 2006, in Victoria, British Columbia, at the age of 90.