The Phoenician city of Ramitha was located in the coastal area where it is the modern port of Latakia, known to the Greeks as Leukê Aktê or "white coast". Laodicea got its name when was first founded in the fourth century BC under the rule of the Seleucid Empire: it was named by Seleucus I Nicator in honor of his mother, Laodice. The city was subsequently ruled by the Romans until the Arab conquest in 637 AD. The RomanPompey the Great conquered the city from the Armenian king Tigranes the Great alongside with all of Syria in 64 BCE and later Julius Caesar declared the city "free polis". During the Severan dynasty, a third centuryimperial dynasty of Rome from Syrian origins, the emperor Septimius Severus named with the title "Metropolis" the city in 194 AD and allowed the Ius Italicum to Laodicea, that was later called a "Roman Colonia". Some Roman merchants moved to live in the city under Augustus, but the city was always culturally "greek" influenced. The Romans made a "Pharum" at the port, that was renowned as one of the best of Ancient Levant; then created a Roman road from southern Anatolia toward Berytus and Damascus, that greatly improved the commerce through the port of Laodicea. The city enjoyed a huge economic prosperity thanks to the wine produced in the hills around the port and exported to all the empire. The city was famous because of the textile products. Laodicea minted coins from an early Roman date, but the most famous are from Severian times. A sizable Jewish population lived in Laodicea during the first century. Under Septimius Severus the city was fortified and was made for a few years the capital of Roman Syria: in this period Laodicea grew to be a city of nearly 40000 inhabitants and had even an hippodrome. Christianity was the main religion in the city after Constantine I and there were many bishops of Laodicea who participated in ecumenical councils, mainly during Byzantine times. The heretic Apollinarius was bishop of Laodicea in the 4th century, when the city was fully Christian but with a few remaining Jews. An earthquake damaged the city in 494 AD and successively Justinian I made Laodicea the capital of the Byzantine province of "Theodorias" in the early sixth century. Laodicea remained its capital for more than a century until the Arab conquest.
Bishops of Laodicea
visited Laodicea and converted the first Christians in the city. Slowly the bishops of Laodicea grew in importance but were always under the Patriarch of Antioch. The most important bishops were:
Lucius of Cyrene, mentionedin Acts, considered first bishop by tradition