Lattice model (biophysics)


Lattice models in biophysics represent a class of statistical-mechanical models which consider a biological macromacromolecule as a lattice of units, each unit being in different states or conformations.
For example, DNA in chromatin can be represented as a one-dimensional lattice, whose elementary units are the nucleotide, base pair or nucleosome. Different states of the unit can be realized either by chemical modifications, or due to quantized internal degrees of freedom, or due to binding events involving a given unit.

DNA-ligand binding models

DNA double helix melting models

DNA coil-globule / fractal models