Leon Pinsker inherited a strong sense of Jewish identity from his father, Simchah Pinsker, a Hebrew language writer, scholar and teacher. Leon attended his father's private school in Odessa and was one of the first Jews to attend Odessa University, where he studied law. Later he realized that, being a Jew, he had no chance of becoming a lawyer due to strict quotas on Jewish professionals and chose the career of a physician.
Jewish and Zionist activism
Pinsker believed that the Jewish problem could be resolved if the Jews attained equal rights. In his early years, Pinsker favored the assimilation path and was one of the founders of a Russian languageJewish weekly. The Odessa pogrom of 1871 moved Pinsker to become an active public figure. In 1881, a bigger wave of anti-Jewish hostilities, many state-sponsored, swept southern Russia and continued until 1884. Then Pinsker's views changed radically, and he no longer believed that mere humanism and Enlightenment would defeat antisemitism. In 1884, he organized an international conference of Hibbat Zion in Katowice. His visit to Western Europe led to his famous pamphlet Auto-Emancipation, subtitled Mahnruf an seine Stammgenossen, von einem russischen Juden, which he published anonymously in German on 1 January 1882, and in which he urged the Jewish people to strive for independence and national consciousness. The book raised strong responses, both for and against. As a professional physician, Pinsker preferred the medical term "Judeophobia" to the recently introduced "antisemitism". Pinsker knew that a combination of mutually exclusive assertions is a characteristic of a psychological disorder and was convinced that pathological, irrational phobia may explain this millennia-old hatred:
: "... to the living the Jew is a corpse, to the native a foreigner, to the homesteader a vagrant, to the proprietary a beggar, to the poor an exploiter and a millionaire, to the patriot a man without a country, for all a hated rival."
In 1890, the Russian authorities approved the establishment of the Society for the Support of Jewish Farmers and Artisans in Syria and Palestine, dedicated to the practical aspects of establishing Jewish agricultural colonies there. Pinsker headed this charity organization, known as the Odessa Committee. Disagreements between various Jewish religious and secular factions, an internal movement crisis and the ban by the Ottoman Empire on Jewish immigration in the 1890s caused Pinsker to doubt whether Eretz Israel would ever become the solution.