Leopold was born at Dessau as the eldest son of the later Leopold II, Prince of Anhalt-Dessau, by his wife Gisela Agnes, daughter of Leopold, Prince of Anhalt-Köthen. After having lost both parents in 1751, the eleven-year-old Leopold inherited Anhalt-Dessau under the regency of his uncle, Prince Dietrich. Following in the footsteps of his grandfather and father, Leopold joined the Prussian army. After the Battle of Kolín, he was impressed so negatively by the spectacle of warfare that he resigned from the army and declared the neutrality of Anhalt-Dessau.
Rule
In 1758 he was declared of age and assumed the government of his lands. An Anglophile and strong supporter of the Enlightenment, Leopold took special interest in the education of the population of his principality in science and nature. His numerous reforms in the areas of education, health care, social services, roads, agriculture, forestry, and industry made Anhalt-Dessau one of the most modern and prosperous of the small German states. The most conspicuous of his improvements included planting fruit trees along dykes and the construction of beautiful buildings. However his reforms included public works programs repairing dykes destroyed by flooding, providing social housing, education, sanitation, the first public parks, burial grounds irrespective of social rank, as well as liberal policies towards the Jewish community, including allowing for the founding of a Jewish school and the first Jewish newspaper in Germany. He engaged Friedrich Wilhelm von Erdmannsdorff to build Wörlitz Palace, the first Neoclassical building in Germany. In 1774 Leopold engaged von Erdmannsdorff to construct a small residence with a small English park as a gift to his wife; in her honor, the castle took the name Schloss Luisium. Leopold also extended and altered the old gardens of Oranienbaum that were laid out in Dutch style to create the first and largest of the English parks of his time, renamed the Dessau-Wörlitz Garden Realm. In 1782 Leopold was tried by the Fürstenbund for his opposition to Prussian hegemony. In 1806 he was invited to Paris by Napoleon, who was impressed by his reputation. Leopold was one of the last princes to join the Confederation of the Rhine on 18 April 1807. On the other hand, despite his differences with the Prussian crown, he offered the Prussian official Ferdinand von Schill an honorable reception in Dessau in 1809. Leopold was elevated to the rank of duke in 1807. As the head of the senior Anhalt branch, he could not earlier by etiquette receive his kinsmen, the Princes of Anhalt-Köthen and Anhalt-Bernburg, who were raised to that rank before him. He received the title by paying a considerable sum of money to the Emperor shortly before the dissolution of the Holy Roman Empire in 1806, just as the prince of Anhalt-Bernburg had done before him. In 1812 Leopold became regent of the duchy of Anhalt-Köthen during the minority of Duke Louis Augustus Karl Frederick Emil. Leopold died after a fall from his horse at Schloss Luisium, near Dessau, in 1817. He was succeeded by his eldest grandson Leopold IV, because his son, the Hereditary Prince Frederick, had predeceased him.
With Johanna Eleonore Hoffmeyer, by marriage von Neitschütz since 1765:
Wilhelmine Eleonore Fredericka.
Count Franz John George of Waldersee, married in Dessau on 20 May 1787 to Countess Louise of Anhalt. They had six children, three sons and three daughters. Their descendants through the eldest son Franz Henry are still alive. A descendant of Franz Heinrich and Bertha von Hünerbein was General Alfred von Waldersee.
Louise Eleonore Fredericka.
With Leopoldine Luise Schoch, daughter of his Master Gardener, who was ennobled with the surname "von Beringer":
Wilhelmine Sidonie von Beringer, married in Wörlitz on 20 June 1815 to Wilhelm von Goerne.
Louise Adelheid von Beringer, married in Wörlitz on 19 August 1812 to Friedrich Ludwig Wilhelm Georg von Glafey.
Franz Adolf von Beringer, married to Auguste Wilhelmine Roeser. They had one son Wilhelm, and one granddaughter, Magda, with the line apparently becoming extinct.
With Johanna Magdalena Luise Jäger :
Franziska.
Leopoldine.
Amalie.
With Fredricka Wilhelmine Schulz, by marriage Favreau:
