| Rank | Title | Studio | Actor | Director | Gross |
| 1. | Black Panther | Walt Disney Studios | Chadwick Boseman, Michael B. Jordan, Lupita Nyong'o, Danai Gurira, Martin Freeman, Daniel Kaluuya, Letitia Wright, Winston Duke, Angela Bassett, Forest Whitaker and Andy Serkis | Ryan Coogler | $700,059,566 |
| 2. | ' | Walt Disney Studios | Robert Downey Jr., Chris Hemsworth, Mark Ruffalo, Chris Evans, Scarlett Johansson, Benedict Cumberbatch, Don Cheadle, Tom Holland, Chadwick Boseman, Paul Bettany, Elizabeth Olsen, Anthony Mackie, Sebastian Stan, Danai Gurira, Letitia Wright, Dave Bautista, Zoe Saldana, Josh Brolin and Chris Pratt | Russo brothers| | $678,815,482 |
| 3. | Incredibles 2 | Walt Disney Studios | voices of Craig T. Nelson, Holly Hunter, Sarah Vowell, Huckleberry Milner and Samuel L. Jackson | Brad Bird | $608,581,744 |
| 4. | ' | Universal Pictures | Chris Pratt, Bryce Dallas Howard, Rafe Spall, Toby Jones, Ted Levine, BD Wong and Jeff Goldblum | J. A. Bayona | $417,719,760 |
| 5. | Deadpool 2 | 20th Century Fox | Ryan Reynolds, Josh Brolin, Morena Baccarin, Julian Dennison, Zazie Beetz, T.J. Miller, Brianna Hildebrand and Jack Kesy | David Leitch | $318,482,400 |
| 6. | The Grinch | Universal Pictures | voices of Benedict Cumberbatch, Rashida Jones, Kenan Thompson, Cameron Seely and Angela Lansbury | Scott Mosier and Yarrow Cheney | $266,280,410 |
| 7. | ' | Sony Pictures | Dwayne Johnson, Jack Black, Kevin Hart, Karen Gillan, Nick Jonas and Bobby Cannavale | Jake Kasdan | $235,512,923 |
| 8. | ' | Paramount Pictures | Tom Cruise, Henry Cavill, Ving Rhames, Simon Pegg, Rebecca Ferguson, Sean Harris, Angela Bassett, Michelle Monaghan and Alec Baldwin | Christopher McQuarrie | $220,159,104 |
| 9. | Ant-Man and the Wasp | Walt Disney Studios | Evangeline Lilly, Michael Peña, Walton Goggins, Bobby Cannavale, Judy Greer, Tip "T.I." Harris, David Dastmalchian, Hannah John-Kamen, Abby Ryder Fortson, Randall Park, Michelle Pfeiffer, Laurence Fishburne and Michael Douglas | Peyton Reed | $216,648,740 |
| 10. | ' | Walt Disney Studios | Alden Ehrenreich, Woody Harrelson, Emilia Clarke, Donald Glover, Thandie Newton, Phoebe Waller-Bridge, Joonas Suotamo and Paul Bettany | Ron Howard | $213,767,512''' |
