List of AFL debuts in 2006
This is a listing of Australian rules footballers to have made their debut with a club for the Australian Football League season 2006.
Debuts
| Name | Club | Age at debut | Round debuted | Games | Goals | Notes |
| Jason Porplyzia | 5 | 130 | 181 | |||
| Bernie Vince | 1 | 129 | 80 | |||
| Ivan Maric | 6 | 77 | 28 | |||
| Joel Patfull | 8 | 182 | 24 | |||
| Cheynee Stiller | 3 | 100 | 21 | |||
| Mitch Clark | 1 | 82 | 61 | |||
| Jason Roe | 6 | 50 | 7 | |||
| Scott Harding | 1 | 48 | 15 | |||
| Rhan Hooper | 2 | 48 | 49 | |||
| Colm Begley | 20 | 29 | 7 | |||
| Ben Fixter | 1 | 27 | 3 | Previously played for Sydney. | ||
| Wayde Mills | 2 | 16 | 3 | |||
| Martin Pask | 11 | 8 | 4 | |||
| Marc Murphy | 1 | 214 | 157 | Son of John Murphy. | ||
| Paul Bower | 21 | 45 | 2 | |||
| Luke Blackwell | 8 | 23 | 4 | Son of Wayne Blackwell. | ||
| Josh Kennedy | 6 | 22 | 11 | |||
| Jason Saddington | 7 | 20 | 6 | Previously played for Sydney. | ||
| Dylan McLaren | 1 | 13 | 4 | Previously played for Brisbane. | ||
| Ryan Jackson | 22 | 9 | 3 | |||
| Jesse D. Smith | 20 | 2 | 0 | |||
| Scott Pendlebury | 10 | 236 | 152 | |||
| Dale Thomas | 1 | 157 | 121 | |||
| Sam Iles | 18 | 7 | 0 | |||
| Patrick Ryder | 1 | 170 | 117 | |||
| Courtenay Dempsey | 7 | 133 | 35 | |||
| Sam Lonergan | 15 | 79 | 39 | |||
| Scott Camporeale | 1 | 19 | 5 | Previously played for Carlton. | ||
| Richard Cole | 17 | 7 | 0 | Previously played for Collingwood. | ||
| Andrew Lee | 13 | 5 | 2 | |||
| Ben Jolley | 15 | 4 | 0 | |||
| Paul Duffield | 5 | 171 | 33 | |||
| Marcus Drum | 13 | 22 | 6 | Son of Damian Drum. | ||
| Adam Campbell | 10 | 13 | 13 | |||
| Michael Warren | 7 | 1 | 0 | |||
| Mathew Stokes | 9 | 189 | 203 | |||
| Brent Prismall | 5 | 25 | 15 | |||
| Ryan Gamble | 22 | 24 | 31 | |||
| Matthew Spencer | 11 | 2 | 0 | |||
| Grant Birchall | 1 | 240 | 33 | |||
| Brent Guerra | 1 | 159 | 25 | Previously played for Port Adelaide and St Kilda. | ||
| Ben McGlynn | 10 | 44 | 28 | |||
| Max Bailey | 18 | 43 | 10 | |||
| Beau Dowler | 18 | 16 | 11 | |||
| Andrew Swallow | 8 | 208 | 76 | |||
| Josh Gibson | 1 | 65 | 2 | |||
| Kasey Green | 1 | 39 | 15 | Previously played for West Coast. | ||
| Ed Lower | 16 | 34 | 15 | Brother of Nick Lower. | ||
| Ben Schwarze | 7 | 11 | 2 | Brother of Troy Schwarze. | ||
| Jonathan Hay | 1 | 8 | 0 | Previously played for Hawthorn. | ||
| Joel Perry | 2 | 8 | 0 | |||
| Cameron Thurley | 1 | 5 | 0 | Previously played for Geelong. | ||
| Daniel McConnell | 19 | 4 | 0 | Previously played for West Coast. | ||
| Jade Rawlings | 10 | 3 | 2 | Previously played for Hawthorn and the Western Bulldogs. Brother of Brady Rawlings. | ||
| Brad Moran | 21 | 3 | 0 | |||
| Nathan Jones | 17 | 223 | 105 | |||
| Lynden Dunn | 6 | 165 | 97 | |||
| Clint Bartram | 1 | 103 | 17 | |||
| Matthew Bate | 5 | 102 | 98 | |||
| Matthew Warnock | 3 | 51 | 1 | |||
| Byron Pickett | 1 | 29 | 16 | Previously played for Kangaroos and Port Adelaide. | ||
| Alipate Carlile | 16 | 167 | 5 | |||
| Tom Logan | 15 | 114 | 27 | Previously played for Brisbane. | ||
| Daniel Motlop | 1 | 83 | 155 | Previously played for Kangaroos. Brother of Shannon Motlop. | ||
| Nathan Lonie | 2 | 40 | 16 | Previously played for Hawthorn. Brother of Ryan Lonie. | ||
| Matt Thomas | 14 | 29 | 7 | |||
| Greg Bentley | 19 | 21 | 6 | |||
| Nick Lower | 19 | 20 | 0 | Brother of Ed Lower. | ||
| Fabian Deluca | 8 | 11 | 1 | Brother of Adrian Deluca. | ||
| James Ezard | 8 | 4 | 1 | |||
| Ryan Willits | 20 | 3 | 1 | |||
| Elijah Ware | 8 | 2 | 1 | |||
| Luke McGuane | 7 | 105 | 39 | |||
| Matthew White | 10 | 105 | 54 | |||
| Dean Polo | 6 | 56 | 11 | |||
| Patrick Bowden | 1 | 25 | 15 | Previously played for Western Bulldogs. Son of Michael Bowden. Brother of Sean and Joel Bowden. | ||
| Cameron Howat | 18 | 21 | 10 | |||
| Cleve Hughes | 5 | 16 | 23 | |||
| Jarrad Oakley-Nicholls | 6 | 13 | 1 | |||
| Jeremy Humm | 3 | 1 | 0 | Previously played for West Coast. | ||
| Sam Gilbert | 8 | 179 | 36 | |||
| Michael Rix | 11 | 29 | 3 | |||
| Fergus Watts | 1 | 1 | 1 | Previously played for Adelaide. | ||
| Ted Richards | 1 | 228 | 15 | Previously played for Essendon. | ||
| Heath Grundy | 16 | 70 | 18 | |||
| Tim Schmidt | 17 | 17 | 12 | |||
| Paul Chambers | 1 | 12 | 0 | Previously played for Geelong. | ||
| Simon Phillips | 15 | 5 | 2 | |||
| Matt Priddis | 10 | 219 | 67 | |||
| Shannon Hurn | 5 | 200 | 49 | |||
| Steven Armstrong | 13 | 36 | 27 | Previously played for Melbourne. | ||
| Shaun Higgins | Western Bulldogs | 9 | 129 | 128 | ||
| Damien McCormack | Western Bulldogs | 15 | 4 | 0 | ||
| Travis Baird | Western Bulldogs | 16 | 3 | 4 | Previously played for Brisbane. |