List of American films of 2010
A list of American films released to cinemas in 2010.
| Title | Director | Cast | Genre | Notes |
| 127 Hours | Danny Boyle | James Franco, Amber Tamblyn, Kate Mara, Clémence Poésy, Lizzy Caplan | Biography, Drama | Fox Searchlight Pictures Adapted from Between a Rock and a Hard Place by Aron Ralston |
| ' | Reed Cowan | The Church of Jesus Christ of Latter-day Saints' involvement in the 2008 California Proposition 8. Narrated by Dustin Lance Black. | Documentary | Red Flag Releasing |
| The Abandoned | Adis Bakrač | Mira Furlan, Tony Grga | Drama | Summer Hill Films |
| The A-Team | Joe Carnahan | Liam Neeson, Bradley Cooper, Quinton "Rampage" Jackson, Sharlto Copley, Jessica Biel, Patrick Wilson, Brian Bloom | Action, Adventure | 20th Century Fox Based on the television series of the same name. |
| A Little Help | Michael J. Weithorn | Jenna Fischer, Chris O'Donnell, Rob Benedict, Arden Myrin, Daniel Yelsky | Comedy | Secret Handshake Entertainment |
| Adventures of Power | Ari Gold | Ari Gold, Michael McKean, Jane Lynch, Shoshannah Stern, Chiu Chi Ling, Adrian Grenier | Comedy | Variance Films |
| Alice in Wonderland | Tim Burton | Johnny Depp, Anne Hathaway, Helena Bonham Carter, Mia Wasikowska, Alan Rickman, Crispin Glover, Stephen Fry, Michael Sheen, Christopher Lee | Family, Fantasy | Walt Disney Pictures Based on the novel of the same name by Lewis Carroll |
| All Good Things | Andrew Jarecki | Ryan Gosling, Kirsten Dunst, Frank Langella, Kristen Wiig, Philip Baker Hall | Mystery | Magnolia Pictures |
| All My Friends Are Funeral Singers | Tim Rutili | Angela Bettis, Emily Candini, Reid Coker | Fantasy | IndiePix Films, Better Angel Films |
| Alpha and Omega | Anthony Bell, Ben Gluck | Justin Long, Hayden Panettiere, Dennis Hopper, Danny Glover, Christina Ricci | Animated, Comedy, Drama, Family | Lionsgate, Crest Animation Productions |
| The American | Anton Corbijn | George Clooney, Violante Placido, Thekla Reuten, Paolo Bonacelli | Drama, Thriller | Focus Features Based on A Very Private Gentleman by Martin Booth |
| The Back-up Plan | Alan Poul | Jennifer Lopez, Alex O'Loughlin, Eric Christian Olsen, Anthony Anderson, Linda Lavin | Romantic comedy | CBS Films |
| Barry Munday | Chris D'Arienzo | Patrick Wilson, Judy Greer, Chloë Sevigny, Jean Smart, Cybill Shepherd, Shea Whigham, Missi Pyle, Christopher McDonald, Billy Dee Williams, Malcolm McDowell | Comedy | Magnolia Pictures Based on Life is a Strange Place by Frank Turner Hollon |
| BearCity | Doug Langway | Gerald McCullouch, Joe Conti, Stephen Guarino, Ashlie Atkinson | LGBT-themed comedy-drama | |
| Big Money Rustlas | Paul Andresen | Insane Clown Posse, Twiztid, Jason Mewes, Mark Jury | Comedy, Western | Psychopathic Direct-to-DVD; preceded by Big Money Hustlas |
| ' | James Nguyen | Alan Bagh, Whitney Moore, Janae Caster, Colton Osborne, Adam Sessa | Romance, horror | Moviehead Pictures |
| Black Swan | Darren Aronofsky | Natalie Portman, Vincent Cassel, Mila Kunis, Barbara Hershey, Winona Ryder | Psychological thriller | Fox Searchlight Pictures |
| Blue Valentine | Derek Cianfrance | Ryan Gosling, Michelle Williams | Romantic drama | The Weinstein Company I spit in your grave |
| The Book of Eli | Albert and Allen Hughes | Denzel Washington, Gary Oldman, Mila Kunis, Ray Stevenson, Jennifer Beals, Frances de la Tour, Michael Gambon | Action, Thriller | Alcon Entertainment, Silver Pictures, Warner Bros. Pictures |
| Bouncing Cats | Nabil Elderkin | Crazy Legs, Abraham "Abramz" Tekya, Common, Mos Def, will.i.am, K'naan | Documentary | Red Bull Media House About hip-hop/b-boy culture improving the lives of children in Uganda. |
| The Bounty Hunter | Andy Tennant | Jennifer Aniston, Gerard Butler | Action comedy | Columbia Pictures |
| Brooklyn's Finest | Antoine Fuqua | Richard Gere, Don Cheadle, Ethan Hawke, Wesley Snipes | Crime drama | Overture Films |
| ' | Chip Mabry | Grace Lightning, Marollin’ Monroe, Madame Bumpsalot | Documentary | Cinema Purgatorio |
| Buried | Rodrigo Cortés | Ryan Reynolds | Thriller | Lionsgate |
| Burlesque | Steve Antin | Cher, Christina Aguilera, Stanley Tucci, Eric Dane, Kristen Bell, Cam Gigandet, Alan Cumming, Julianne Hough, Peter Gallagher | Musical | Screen Gems |
| Case 39 | Christian Alvart | Renée Zellweger, Jodelle Ferland, Ian McShane, Bradley Cooper | Horror, Mystery | Paramount Pictures, Paramount Vantage |
| Casino Jack | George Hickenlooper | Kevin Spacey, Barry Pepper, Kelly Preston, Jon Lovitz, Rachelle Lefevre, Daniel Kash, Graham Greene, Maury Chaykin | Political drama, Thriller | ATO Pictures |
| Casino Jack and the United States of Money | Alex Gibney | Washington D. C. lobbyist Jack Abramoff's corruption scandal. | Documentary | Magnolia Pictures |
| ' | Brad Peyton | Christina Applegate, Michael Clarke Duncan, Neil Patrick Harris, Sean Hayes, James Marsden, Bette Midler, Nick Nolte, Joe Pantoliano, Katt Williams, Chris O'Donnell, Jack McBrayer, Fred Armisen, Paul Rodriguez, Alec Baldwin, Roger Moore | Family, Live-action/animated film | Warner Bros. Pictures, Village Roadshow Pictures Preceded by Cats & Dogs |
| Charlie St. Cloud | Burr Steers | Zac Efron, Amanda Crew, Donal Logue, Charlie Tahan, Ray Liotta, Kim Basinger, Chris Massoglia | Romantic fantasy | Universal Pictures Based on The Death and Life of Charlie St. Cloud by Ben Sherwood |
| ' | Michael Apted | Georgie Henley, Skandar Keynes, Ben Barnes, Liam Neeson, Will Poulter, Simon Pegg | Family, Fantasy | 20th Century Fox Preceded by ' |
| City Island | Raymond De Felitta | Andy García, Julianna Margulies, Steven Strait, Alan Arkin, Emily Mortimer | Comedy-drama | Anchor Bay Films |
| Clash of the Titans | Louis Leterrier | Sam Worthington, Gemma Arterton, Mads Mikkelsen, Alexa Davalos, Jason Flemyng, Nicholas Hoult, Danny Huston, Izabella Miko, Pete Postlethwaite, Polly Walker, Ralph Fiennes, Liam Neeson | Action-adventure, Fantasy | Warner Bros. Pictures, Legendary Pictures Based on the 1981 film of the same name |
| ' | Alex Gibney | The life and career of former New York Governor Eliot Spitzer | Documentary | Magnolia Pictures |
| The Company Men | John Wells | Ben Affleck, Chris Cooper, Kevin Costner, Tommy Lee Jones, Maria Bello, Rosemarie DeWitt, Craig T. Nelson | Drama | The Weinstein Company |
| Conviction | Tony Goldwyn | Hilary Swank, Sam Rockwell, Minnie Driver, Melissa Leo, Peter Gallagher, Juliette Lewis | Biography, Drama | Fox Searchlight Pictures |
| Cop Out | Kevin Smith | Bruce Willis, Tracy Morgan, Adam Brody, Kevin Pollak, Guillermo Diaz, Seann William Scott | Buddy cop, Comedy | Warner Bros. Pictures |
| Countdown to Zero | Lucy Walker | The discussion on the escalating nuclear arms race. Narrated by Gary Oldman | Documentary | Magnolia Pictures |
| Country Strong | Shana Feste | Gwyneth Paltrow, Tim McGraw, Garrett Hedlund, Leighton Meester | Dramedy, Musical | Screen Gems |
| The Crazies | Breck Eisner | Timothy Olyphant, Radha Mitchell, Joe Anderson, Danielle Panabaker | Horror | Overture Films. Based on the 1973 film of the same name |
| Crazy on the Outside | Tim Allen | Tim Allen, Sigourney Weaver, Jeanne Tripplehorn, J. K. Simmons, Julie Bowen, Kelsey Grammer, Ray Liotta | Comedy-drama | Freestyle Releasing |
| Cyrus | Jay and Mark Duplass | John C. Reilly, Jonah Hill, Marisa Tomei, Catherine Keener | Comedy | Fox Searchlight Pictures |
| Date Night | Shawn Levy | Steve Carell, Tina Fey | Action comedy | 20th Century Fox |
| Darkening Sky | Victor Bornia | Rider Strong, Danica Stewart | Thriller | |
| Daybreakers | Michael and Peter Spierig | Ethan Hawke, Willem Dafoe, Isabel Lucas, Sam Neill | Horror | Lionsgate |
| Dead Awake | Omar Naim | Nick Stahl, Rose McGowan, Amy Smart | Mystery | |
| Dear John | Lasse Hallström | Channing Tatum, Amanda Seyfried, Henry Thomas, Scott Porter, Richard Jenkins | Romantic drama | Screen Gems, Relativity Media Based on the novel by Nicholas Sparks |
| Death at a Funeral | Neil LaBute | Loretta Devine, Peter Dinklage, Danny Glover, Regina Hall, Martin Lawrence, James Marsden, Tracy Morgan, Chris Rock, Zoe Saldana, Columbus Short, Luke Wilson | Black comedy | Screen Gems Based on the 2007 British film |
| Despicable Me | Pierre Coffin, Chris Renaud | Steve Carell, Miranda Cosgrove, Jason Segel, Russell Brand, Kristen Wiig, Will Arnett, Ken Jeong, Danny McBride, Julie Andrews | Animated, Family | Universal Pictures, Illumination Entertainment |
| Devil | John Erick Dowdle | Chris Messina, Logan Marshall-Green, Geoffrey Arend, Caroline Dhavernas, Jacob Vargas, Jenny O'Hara, Bojana Novakovic, Joshua Peace, Bokeem Woodbine | Horror, Thriller | Universal Pictures |
| Diary of a Wimpy Kid | Thor Freudenthal | Zachary Gordon, Robert Capron, Rachel Harris, Steve Zahn, Devon Bostick, Chloë Grace Moretz | Comedy, Family | 20th Century Fox Based on the book by Jeff Kinney |
| Dinner for Schmucks | Jay Roach | Steve Carell, Paul Rudd, Jemaine Clement, Jeff Dunham, Zach Galifianakis, Bruce Greenwood, Ron Livingston, Rick Overton, Lucy Punch, Andrea Savage, David Walliams | Comedy | Paramount Pictures, DreamWorks Pictures, Spyglass Entertainment Based on Le Dîner de Cons |
| Dirty Girl | Abe Sylvia | Juno Temple, Milla Jovovich, Mary Steenburgen, Tim McGraw | Drama | The Weinstein Company |
| Due Date | Todd Phillips | Robert Downey Jr., Zach Galifianakis, Michelle Monaghan, Juliette Lewis, Jamie Foxx, RZA, Alan Arkin, Matt Walsh, Danny McBride | Comedy, Road | Warner Bros. Pictures |
| Easy A | Will Gluck | Emma Stone, Penn Badgley, Amanda Bynes, Thomas Haden Church, Patricia Clarkson, Cam Gigandet, Lisa Kudrow, Malcolm McDowell, Aly Michalka | Comedy, Teen | Screen Gems |
| Eat Pray Love | Ryan Murphy | Julia Roberts, James Franco, Richard Jenkins, Viola Davis, Billy Crudup, Javier Bardem | Comedy-drama | Columbia Pictures Based on the memoir of the same name by Elizabeth Gilbert |
| ' | David Slade | Kristen Stewart, Robert Pattinson, Taylor Lautner, Ashley Greene, Peter Facinelli, Elizabeth Reaser, Kellan Lutz, Nikki Reed, Catalina Sandino Moreno, Jackson Rathbone, Bryce Dallas Howard, Billy Burke, Jodelle Ferland, Dakota Fanning, Xavier Samuel, Julia Jones, Jack Huston | Fantasy romance | Summit Entertainment Based on Eclipse by Stephenie Meyer Preceded by New Moon |
| Edge of Darkness | Martin Campbell | Mel Gibson, Ray Winstone, Danny Huston, Bojana Novakovic, Shawn Roberts, Gbenga Akinnagbe | Action drama | Based on the television series of the same name |
| The Expendables | Sylvester Stallone | Sylvester Stallone, Jason Statham, Jet Li, Dolph Lundgren, Eric Roberts, Randy Couture, Steve Austin, David Zayas, Giselle Itié, Charisma Carpenter, Gary Daniels, Terry Crews, Mickey Rourke, Bruce Willis, Arnold Schwarzenegger | Action | Lionsgate |
| The Extra Man | Shari Springer Berman and Robert Pulcini | Kevin Kline, Paul Dano, Katie Holmes, John C. Reilly | Comedy | Magnolia Pictures. Based on the novel by Jonathan Ames |
| Extraordinary Measures | Tom Vaughan | Brendan Fraser, Harrison Ford, Keri Russell | Drama | CBS Films |
| Fair Game | Doug Liman | Naomi Watts, Sean Penn | Biography, Spy thriller | Summit Entertainment Based on The Politics of Truth by Joseph Wilson and ' by Valerie Plame |
| Faster | George Tillman Jr. | Dwayne Johnson, Billy Bob Thornton, Carla Gugino, Maggie Grace, Oliver Jackson-Cohen, Moon Bloodgood | Action drama | CBS Films |
| The Fighter | David O. Russell | Mark Wahlberg, Christian Bale, Amy Adams, Melissa Leo | Drama, Sports | Paramount Pictures, Relativity Media |
| Flipped | Rob Reiner | Madeline Carroll, Rebecca De Mornay, Anthony Edwards, John Mahoney, Callan McAuliffe, Penelope Ann Miller, Aidan Quinn, Kevin Weisman | Romantic comedy | Warner Bros. Pictures Based on the novel of the same name by Wendelin Van Draanen |
| For Colored Girls | Tyler Perry | Janet Jackson, Thandie Newton, Whoopi Goldberg, Phylicia Rashad, Anika Noni Rose, Loretta Devine, Kimberly Elise, Kerry Washington | Drama | Lionsgate Based on the stage play For Colored Girls Who Have Considered Suicide When the Rainbow Is Enuf by Ntozake Shange |
| Freakonomics | Heidi Ewing, Rachel Grady, Alex Gibney, Seth Gordon, Eugene Jarecki, Morgan Spurlock | A group of rogue filmmakers explore the hidden side of everything. | Documentary | Magnolia Pictures. Based on the book by Steven Levitt and Stephen Dunbar |
| From Paris with Love | Pierre Morel | John Travolta, Jonathan Rhys Meyers | Action | Lionsgate |
| Frozen | Adam Green | Kevin Zegers, Shawn Ashmore, Emma Bell | Horror | Anchor Bay Films |
| Furry Vengeance | Roger Kumble | Brendan Fraser, Brooke Shields, Dick Van Dyke, Ken Jeong, Rob Riggle, Angela Kinsey, Matt Prokop | Comedy, Family | Summit Entertainment |
| Game of Death | Giorgio Serafini | Wesley Snipes, Zoë Bell, Gary Daniels, Robert Davi, Ernie Hudson, Jaime Moyer, Frank Zieger | Action | Stage 6 Films, Sony Pictures Home Entertainment |
| Generation Zero | Steve Bannon | the financial crisis of 2007–2008 in the context of a generational theory | Documentary | Citizens United |
| Get Him to the Greek | Nicholas Stoller | Jonah Hill, Russell Brand, Elisabeth Moss, Rose Byrne, Colm Meaney, Sean Combs | Comedy | Universal Pictures, Relativity Media, Spyglass Entertainment |
| Get Low | Aaron Schneider | Robert Duvall, Bill Murray, Sissy Spacek, Lucas Black | Drama | Sony Pictures Classics |
| Going the Distance | Nanette Burstein | Drew Barrymore, Charlie Day, Jason Sudeikis, Ron Livingston, Rob Riggle, Christina Applegate, Kelli Garner, Natalie Morales, June Diane Raphael, Kristen Schaal, Jim Gaffigan, Sarah Burns | Romantic comedy | New Line Cinema |
| The Good Guy | Julio DePietro | Scott Porter, Alexis Bledel, Bryan Greenberg, Aaron Yoo, Anna Chlumsky, Kate Nauta, Andrew McCarthy | Drama, Romantic comedy | Roadside Attractions |
| The Greatest | Shana Feste | Pierce Brosnan, Susan Sarandon, Carey Mulligan, Johnny Simmons, Aaron Johnson, Zoë Kravitz, Michael Shannon | Drama | Barbarian Film Group |
| Green Zone | Paul Greengrass | Matt Damon, Greg Kinnear, Brendan Gleeson, Amy Ryan, Khalid Abdalla, Jason Isaacs | Action, Spy film | Universal Pictures Based on Imperial Life in the Emerald City by Rajiv Chandrasekaran |
| Greenberg | Noah Baumbach | Ben Stiller, Greta Gerwig, Rhys Ifans, Jennifer Jason Leigh, Mark Duplass, Chris Messina, Brie Larson, Juno Temple | Comedy | Focus Features |
| Grown Ups | Dennis Dugan | Adam Sandler, Kevin James, Chris Rock, Rob Schneider, David Spade | Comedy | Columbia Pictures |
| Gulliver's Travels | Rob Letterman | Jack Black, Emily Blunt, Jason Segel, Catherine Tate, James Corden, Amanda Peet, Chris O'Dowd, Billy Connolly, Hugh Jackman | Comedy, Family | 20th Century Fox Based on the 18th-century novel of the same name by Jonathan Swift |
| Happy Tears | Mitchell Lichtenstein | Parker Posey, Demi Moore, Rip Torn, Ellen Barkin | Dramedy | Roadside Attractions |
| ' | Lasse Hallström | Richard Gere | Drama | Remake of the 1987 Japanese film Hachikō Monogatari |
| Harry Potter and the Deathly Hallows: Part 1 | David Yates | Daniel Radcliffe, Rupert Grint, Emma Watson, Helena Bonham Carter, Robbie Coltrane, Warwick Davis, Ralph Fiennes, Michael Gambon, Brendan Gleeson, Richard Griffiths, John Hurt, Jason Isaacs, Alan Rickman, Fiona Shaw, Timothy Spall, Imelda Staunton, David Thewlis, Julie Walters | Action-adventure, Fantasy | Warner Bros. Pictures Preceded by Harry Potter and the Half-Blood Prince |
| Hereafter | Clint Eastwood | Matt Damon, Cécile de France, Bryce Dallas Howard, Lyndsey Marshal, Jay Mohr, Thierry Neuvic, Jenifer Lewis | Drama | Warner Bros. Pictures |
| Holy Rollers | Kevin Asch | Jesse Eisenberg, Justin Bartha, Ari Graynor, Danny A. Abeckaser, Q-Tip, Jason Fuchs | Drama | First Independent Pictures |
| Hot Tub Time Machine | Steve Pink | John Cusack, Rob Corddry, Craig Robinson, Clark Duke, Crispin Glover, Lizzy Caplan, Chevy Chase | Comedy, Science fiction | MGM Pictures, United Artists |
| How Do You Know | James L. Brooks | Reese Witherspoon, Owen Wilson, Paul Rudd, Jack Nicholson | Romantic comedy | Columbia Pictures |
| How to Train Your Dragon | Chris Sanders, Dean DeBlois | Jay Baruchel, Gerard Butler, Craig Ferguson, America Ferrera, Jonah Hill, Christopher Mintz-Plasse, T. J. Miller, Kristen Wiig | Family, Fantasy | DreamWorks Animation, Paramount Pictures |
| Hubble 3D | Toni Myers | The Hubble Space Telescope repair mission. Narrated by Leonardo DiCaprio. | Documentary | Warner Bros. Pictures |
| Hurricane Season | Tim Story | Forest Whitaker, Lil Wayne, Bow Wow, Isaiah Washington, Taraji P. Henson, Michael Gaston, Jackie Long, Khleo Thomas | Drama, Sports | Dimension Films, The Weinstein Company Direct-to-DVD |
| Hyenas | Eric Weston | Christa Campbell, Costas Mandylor, Joshua Alba, Rudolf Martin | Horror | Entertainment Dome |
| I Love You Phillip Morris | John Requa and Glenn Ficarra | Jim Carrey, Ewan McGregor, Leslie Mann, Rodrigo Santoro | Bio-pic, Comedy-drama | Roadside Attractions Adapted from the book by Steve McVicker |
| I'm Still Here | Casey Affleck | Tumultuous year in the life of actor Joaquin Phoenix as he attempts to reinvent himself as a hip-hop artist. | Mockumentary | Magnolia Pictures |
| Inception | Christopher Nolan | Leonardo DiCaprio, Ken Watanabe, Joseph Gordon-Levitt, Marion Cotillard, Ellen Page, Tom Hardy, Cillian Murphy, Tom Berenger, Michael Caine | Science fiction | Warner Bros. Pictures |
| Iron Man 2 | Jon Favreau | Robert Downey Jr., Don Cheadle, Mickey Rourke, Gwyneth Paltrow, Sam Rockwell, Scarlett Johansson, Samuel L. Jackson | Superhero | Paramount Pictures, Marvel Entertainment Preceded by Iron Man |
| It's Kind of a Funny Story | Ryan Fleck and Anna Boden | Keir Gilchrist, Zach Galifianakis, Emma Roberts, Viola Davis, Zoë Kravitz, Aasif Mandvi, Lauren Graham, Jim Gaffigan | Comedy-drama | Focus Features Based on the novel of the same name by Ned Vizzini |
| Jack Goes Boating | Philip Seymour Hoffman | Philip Seymour Hoffman, Amy Ryan, John Ortiz, Daphne Rubin-Vega | Romantic comedy | Overture Films. Based on the play by Bob Glaudini |
| Jackass 3-D | Jeff Tremaine | Johnny Knoxville, Bam Margera, Chris Pontius, Steve-O, Ryan Dunn, Dave England, Jason "Wee Man" Acuña, Ehren McGhehey, Preston Lacy, The Dudesons | Comedy | Paramount Pictures, MTV Films Preceded by Jackass Number Two |
| Jonah Hex | Jimmy Hayward | Josh Brolin, John Malkovich, Megan Fox, Michael Fassbender, Will Arnett, Michael Shannon | Superhero, Western | Warner Bros. Pictures, Legendary Pictures Based on the DC Comics character |
| The Joneses | Derrick Börte | David Duchovny, Demi Moore, Amber Heard, Ben Hollingsworth, Gary Cole, Glenne Headly, Lauren Hutton | Drama comedy | Roadside Attractions |
| Just Wright | Sanaa Hamri | Queen Latifah, Common, Paula Patton | Romantic comedy | Fox Searchlight Pictures |
| Kaboom | Gregg Araki | Roxane Mesquida, Thomas Dekker, Juno Temple, Haley Bennett, James Duval | Science fiction | Crispy Films |
| The Karate Kid | Harald Zwart | Jaden Smith, Jackie Chan, Taraji P. Henson | Martial arts | Columbia Pictures, Overbrook Entertainment Preceded by The Next Karate Kid |
| Kick-Ass | Matthew Vaughn | Aaron Johnson, Christopher Mintz-Plasse, Chloë Grace Moretz, Mark Strong, Nicolas Cage | Superhero | Lionsgate Based on the comic by Mark Millar and John S. Romita, Jr. |
| The Kids Are All Right | Lisa Cholodenko | Annette Bening, Julianne Moore, Mark Ruffalo, Mia Wasikowska, Josh Hutcherson | Comedy | Focus Features |
| The Killer Inside Me | Michael Winterbottom | Casey Affleck, Kate Hudson, Jessica Alba, Ned Beatty, Elias Koteas, Tom Bower, Simon Baker, Bill Pullman | Crime drama | IFC Films Based on the novel of the same name by Jim Thompson |
| Killers | Robert Luketic | Katherine Heigl, Ashton Kutcher | Action comedy | Lionsgate |
| Knight and Day | James Mangold | Tom Cruise, Cameron Diaz, Maggie Grace, Peter Sarsgaard, Paul Dano, Viola Davis | Action-comedy | 20th Century Fox |
| Knucklehead | Michael Watkins | Mark Feuerstein, Melora Hardin, Big Show, Dennis Farina, Wendie Malick, Rebecca Creskoff, Bobb'e J. Thompson, Will Patton, Saul Rubinek | Comedy | Samuel Goldwyn Films, WWE Studios |
| The Last Airbender | M. Night Shyamalan | Noah Ringer, Nicola Peltz, Jackson Rathbone, Dev Patel, Shaun Toub, Aasif Mandvi, Cliff Curtis, Jessica Andres, Katharine Houghton, Seychelle Gabriel | Action-adventure, Fantasy, Family | Paramount Pictures, Nickelodeon Movies. Based on the animated show ' |
| The Last Exorcism | Daniel Stamm | Patrick Fabian, Iris Bahr, Louis Herthum, Ashley Bell, Jamie Alyson Caulde, Tony Bentley, Shanna Forrestall, Allen Boudreaux, Caleb Landry Jones | Horror | Lionsgate |
| The Last Song | Julie Anne Robinson | Miley Cyrus, Liam Hemsworth, Bobby Coleman, Kelly Preston, Greg Kinnear | Dramedy, Romance | Touchstone Pictures Based on the novel by Nicholas Sparks |
| Leap Year | Anand Tucker | Amy Adams, Matthew Goode, Adam Scott, John Lithgow | Romantic comedy | Universal Pictures, Spyglass Entertainment |
| ' | Zack Snyder | Jim Sturgess, Geoffrey Rush, Emily Barclay, Anthony LaPaglia, David Wenham, Hugo Weaving, Ryan Kwanten, Helen Mirren, Sam Neill, Joel Edgerton, Miriam Margolyes, Richard Roxburgh, Deborra-Lee Furness, Abbie Cornish, Leigh Whannell, Angus Sampson, Bill Hunter, Sacha Horler, Essie Davis, Barry Otto | Fantasy | Warner Bros. Pictures, Village Roadshow Pictures, Animal Logic Based on the Guardians of Ga'Hoole book series by Kathryn Lasky |
| Legendary | Mel Damski | Patricia Clarkson, John Cena, Devon Graye, Madeleine Martin, Tyler Posey, Danny Glover | Drama | Samuel Goldwyn Films, WWE Studios |
| Legion | Scott Stewart | Paul Bettany, Lucas Black, Tyrese Gibson, Charles S. Dutton, Adrianne Palicki, Kevin Durand, Doug Jones, Willa Holland, Kate Walsh, Dennis Quaid | Action thriller, Fantasy | Screen Gems |
| Let Me In | Matt Reeves | Kodi Smit-McPhee, Chloë Grace Moretz, Elias Koteas, Richard Jenkins | Horror | Overture Films. Based on the novel Let the Right One In and film of the same name by John Ajvide Lindqvist |
| Letters to God | David Nixon | Robyn Lively, Jeffrey Johnson, Tanner Maguire, Bailee Madison, Ralph Waite | Drama | Possibility Pictures |
| Letters to Juliet | Gary Winick | Amanda Seyfried, Chris Egan, Vanessa Redgrave, Gael García Bernal, Franco Nero | Romantic drama | Summit Entertainment |
| Life as We Know It | Greg Berlanti | Katherine Heigl, Josh Duhamel | Romantic comedy | Warner Bros., Village Roadshow Pictures |
| Like Dandelion Dust | Jon Gunn | Mira Sorvino, Barry Pepper, Cole Hauser, Kate Levering, Maxwell Perry Cotton, L. Scott Caldwell | Drama | Downes Brothers Entertainment, Lucky Crow Films |
| Little Fockers | Paul Weitz | Robert De Niro, Ben Stiller, Owen Wilson, Blythe Danner, Teri Polo, Jessica Alba, Laura Dern, Harvey Keitel, Dustin Hoffman, Barbra Streisand | Comedy | Universal Pictures, Paramount Pictures, DreamWorks Pictures Relativity Media Preceded by Meet the Fockers |
| The Losers | Sylvain White | Jeffrey Dean Morgan, Zoe Saldana, Chris Evans, Idris Elba, Columbus Short, Oscar Janaeda, Jason Patric | Action comedy, Superhero | Warner Bros. Pictures, Dark Castle Entertainment Based on the comic book series of the same name. |
| Lottery Ticket | Erik White | Bow Wow, Brandon T. Jackson, Naturi Naughton, Keith David, Charlie Murphy, Gbenga Akinnagbe, Terry Crews, Bill Bellamy, Mike Epps, T-Pain, Loretta Devine, Ice Cube | Comedy | Warner Bros. Pictures, Alcon Entertainment |
| Love Ranch | Taylor Hackford | Helen Mirren, Joe Pesci, Sergio Peris-Mencheta, Gina Gershon, Bryan Cranston | Drama | Summit Entertainment |
| Love & Other Drugs | Edward Zwick | Jake Gyllenhaal, Anne Hathaway, Oliver Platt, Hank Azaria, Josh Gad, Gabriel Macht, Judy Greer, Jill Clayburgh | Comedy-drama | Fox 2000 Pictures, Regency Enterprises. Based on Hard Sell: The Evolution of a Viagra Salesman by Jamie Reidy |
| MacGruber | Jorma Taccone | Will Forte, Kristen Wiig, Ryan Phillippe, Powers Boothe, Maya Rudolph, Derek Mears, Val Kilmer, Mark Henry, Chris Jericho, Glenn Jacobs, Paul Wight, Montel Vontavious Porter, The Great Khali | Action-comedy, Parody | Rogue Pictures Based on the recurring Saturday Night Live sketch of the same name. |
| Machete | Robert Rodriguez, Ethan Maniquis | Danny Trejo, Michelle Rodriguez, Cheech Marin, Jeff Fahey, Lindsay Lohan, Don Johnson, Jessica Alba, Steven Seagal, Robert De Niro, Daryl Sabara, Tom Savini | Action | 20th Century Fox, Troublemaker Studios |
| Marmaduke | Tom Dey | Owen Wilson, George Lopez, Lee Pace, Judy Greer, David Walliams, William H. Macy, Steve Coogan, Sam Elliott, Fergie, Jeremy Piven, Christopher Mintz-Plasse, Emma Stone, Kiefer Sutherland, Damon Wayans Jr., Marlon Wayans | Family, Live-action | 20th Century Fox, Regency Enterprises |
| Marwencol | Jeff Malmberg | After a vicious attack leaves him brain-damaged and broke; Mark Hogancamp seeks recovery in "Marwencol" a 1/6th scale World War II-era town he creates in his backyard. | Documentary | The Cinema Guild |
| Meek's Cutoff | Kelly Reichardt | Michelle Williams, Bruce Greenwood, Shirley Henderson, Will Patton, Paul Dano | Western | Evenstar Films |
| Megamind | Tom McGrath | Will Ferrell, Tina Fey, Jonah Hill, David Cross, Brad Pitt | Comedy, Superhero | DreamWorks Animation SKG, Paramount Pictures |
| Middle Men | George Gallo | Luke Wilson, Giovanni Ribisi, Gabriel Macht, James Caan, Jacinda Barrett, Laura Ramsey, Terry Crews, Rade Šerbedžija, Kelsey Grammer, Kevin Pollak, Robert Forster | Comedy-drama, Crime | Paramount Pictures, Paramount Vantage |
| Mirrors 2 | Víctor Garciá | Nick Stahl, Emmanuelle Vaugier, Evan Jones, Christy Carlson Romano, William Katt, Lawrence Turner, Stephanie Honoré, Jon Michael Davis, Jennifer Sipes, Ann Mckenzie | Horror | 20th Century Fox Direct-to-DVD Preceded by Mirrors |
| Morning Glory | Roger Michell | Rachel McAdams, Harrison Ford, Diane Keaton, Patrick Wilson, Jeff Goldblum | Comedy | Paramount Pictures |
| Mother and Child | Rodrigo García | Naomi Watts, Annette Bening, Kerry Washington, Jimmy Smits, Samuel L. Jackson, S. Epatha Merkerson, Cherry Jones, Elpidia Carrillo, Shareeka Epps | Drama | Sony Pictures Classics |
| My Soul to Take | Wes Craven | Max Thieriot, Denzel Whitaker, Raúl Esparza, Shareeka Epps, Zena Grey, Trevor St. John | Horror | Rogue Pictures |
| Nanny McPhee Returns | Susanna White | Emma Thompson, Maggie Gyllenhaal, Rhys Ifans, Maggie Smith, Ralph Fiennes, Ewan McGregor | Family, Fantasy | Universal Pictures, StudioCanal, Relativity Media Preceded by Nanny McPhee |
| The Next Three Days | Paul Haggis | Russell Crowe, Elizabeth Banks, Brian Dennehy, Olivia Wilde, Liam Neeson | Thriller | Lionsgate |
| Night Catches Us | Tanya Hamilton | Anthony Mackie, Kerry Washington | Drama | Magnolia Pictures |
| A Nightmare on Elm Street | Samuel Bayer | Jackie Earle Haley, Rooney Mara, Thomas Dekker, Kellan Lutz, Katie Cassidy, Connie Britton, Clancy Brown | Horror | New Line Cinema, Platinum Dunes Based on the 1984 film of the same name |
| The Other Guys | Adam McKay | Samuel L. Jackson, Mark Wahlberg, Will Ferrell, Dwayne Johnson, Eva Mendes, Anne Heche, Michael Keaton, Steve Coogan, Ray Stevenson | Action comedy | Columbia Pictures |
| Our Family Wedding | Rick Famuyiwa | Forest Whitaker, America Ferrera, Carlos Mencia, Regina King, Lance Gross | Comedy | Fox Searchlight Pictures |
| Paper Man | Kieran and Michelle Mulroney | Jeff Daniels, Emma Stone, Ryan Reynolds, Lisa Kudrow | Comedy-drama | MPI Media Group |
| Paranormal Activity 2 | Tod Williams | Katie Featherston, Micah Sloat, Sprague Grayden, Molly Ephraim | Horror | Paramount Pictures Preceded by Paranormal Activity |
| Passion Play | Mitch Glazer | Mickey Rourke, Megan Fox, Bill Murray, Kelly Lynch | Drama | Annapurna Productions |
| ' | Chris Columbus | Logan Lerman, Brandon T. Jackson, Alexandra Daddario, Jake Abel, Rosario Dawson, Steve Coogan, Uma Thurman, Pierce Brosnan, Sean Bean | Adventure, Family | 20th Century Fox, Fox 2000 Pictures Based on The Lightning Thief by Rick Riordan |
| The Perfect Game | William Dear | Clifton Collins Jr., Cheech Marin, Emilie de Ravin, Moisés Arias, Jake T. Austin, Jansen Panettiere, Lou Gossett Jr., Bruce McGill | Drama | IndustryWorks Based on the book of the same name by W. William Winokur |
| Piranha 3-D | Alexandre Aja | Elisabeth Shue, Adam Scott, Jerry O'Connell, Ving Rhames, Jessica Szohr, Steven R. McQueen, Christopher Lloyd, Richard Dreyfuss, Kelly Brook, Riley Steele, Ricardo Chavira, Paul Scheer | Horror | Dimension Films. Based on the 1978 film of the same name |
| Princess Kaiulani | Marc Forby | Q'orianka Kilcher, Barry Pepper, Will Patton, Julian Glover, Shaun Evans | Biographical drama | Roadside Attractions Premiered at the 2009 Hawaii International Film Festival under the title Barbarian Princess |
| Please Give | Nicole Holofcener | Catherine Keener, Amanda Peet, Oliver Platt, Rebecca Hall, Ann Guilbert, Kevin Corrigan, Sarah Steele | Dark comedy | Sony Pictures Classics |
| Preacher's Kid | Stan Foster | LeToya Luckett, Rae'Ven Larrymore Kelly, Kierra Sheard, Clifton Powell, Gregory Alan Williams | Drama | Gener8Xion Entertainment |
| Predators | Nimród Antal | Adrien Brody, Topher Grace, Alice Braga, Walton Goggins, Oleg Taktarov, Louis Ozawa Changchien, Mahershalalhashbaz Ali, Laurence Fishburne, Danny Trejo | Sci-fi horror | 20th Century Fox, Troublemaker Studios Preceded by Predator 2 |
| ' | Mike Newell | Jake Gyllenhaal, Ben Kingsley, Gemma Arterton, Alfred Molina | Action-adventure, Fantasy | Walt Disney Pictures Based on the of the same name from Ubisoft. |
| Rabbit Hole | John Cameron Mitchell | Nicole Kidman, Aaron Eckhart, Dianne Wiest, Tammy Blanchard, Miles Teller, Giancarlo Esposito, Jon Tenney, Sandra Oh | Drama | Lionsgate Based on the 2007 Tony award-winning play of the same name by David Lindsay-Abaire |
| Ramona and Beezus | Elizabeth Allen | Joey King, Selena Gomez, John Corbett, Bridget Moynahan, Ginnifer Goodwin, Josh Duhamel, Sandra Oh | Comedy, Family | 20th Century Fox, Walden Media Based on Beezus and Ramona by Beverly Cleary |
| The Rebound | Bart Freundlich | Catherine Zeta-Jones, Justin Bartha, Jordan Carlos, Kelly Gould, Art Garfunkel | romantic comedy | Film Department |
| Red | Robert Schwentke | Bruce Willis, Morgan Freeman, John Malkovich, Helen Mirren, Karl Urban, Mary-Louise Parker, Brian Cox, Julian McMahon, Richard Dreyfuss | Action comedy | Summit Entertainment Based on the graphic mini-series of the same name by Warren Ellis and Cully Hamner |
| Remember Me | Allen Coulter | Robert Pattinson, Emilie de Ravin, Chris Cooper, Lena Olin, Pierce Brosnan | Romantic drama | Summit Entertainment |
| Repo Men | Miguel Sapochnik | Jude Law, Forest Whitaker, Liev Schreiber, Alice Braga, Carice van Houten, Chandler Canterbury | Action thriller, Science fiction | Universal Pictures |
| ' | Paul W. S. Anderson | Milla Jovovich, Ali Larter, Kim Coates, Shawn Roberts, Sergio Peris-Mencheta, Spencer Locke, Boris Kodjoe, Wentworth Miller | Action horror, Science fiction | Screen Gems Preceded by ' |
| Robin Hood | Ridley Scott | Russell Crowe, Cate Blanchett, William Hurt, Mark Strong, Mark Addy, Oscar Isaac, Danny Huston, Eileen Atkins, Max von Sydow | Action-adventure | Universal Pictures |
| The Romantics | Galt Niederhoffer | Katie Holmes, Josh Duhamel, Anna Paquin, Malin Åkerman, Adam Brody, Dianna Agron, Jeremy Strong, Rebecca Lawrence, Candice Bergen, Elijah Wood | Romantic comedy | Four of a Kind, Paramount Famous Productions. Based upon the novel of the same name by Galt Niederhoffer |
| The Runaways | Floria Sigismondi | Kristen Stewart, Dakota Fanning, Michael Shannon, Scout Taylor-Compton, Alia Shawkat | Biography, Drama | Apparation |
| Saint John of Las Vegas | Huế Rhodes | Steve Buscemi, Romany Malco, Peter Dinklage, Emmanuelle Chriqui, Tim Blake Nelson, Sarah Silverman | Comedy | IndieVest Pictures |
| Salt | Phillip Noyce | Angelina Jolie, Liev Schreiber, Chiwetel Ejiofor | Action thriller | Columbia Pictures |
| Saw VII | Kevin Greutert | Tobin Bell, Costas Mandylor, Cary Elwes, Betsy Russell, Sean Patrick Flanery | Horror | Lionsgate Preceded by Saw VI Last installment in Saw franchise |
| Scott Pilgrim vs. the World | Edgar Wright | Michael Cera, Mary Elizabeth Winstead, Kieran Culkin, Chris Evans, Anna Kendrick, Alison Pill, Mark Webber, Johnny Simmons, Brandon Routh, Jason Schwartzman, Mae Whitman, Brie Larson, Aubrey Plaza, Tennessee Thomas | Action, Romantic comedy | Universal Pictures Based on the Scott Pilgrim novels by Bryan Lee O'Malley |
| Secretariat | Randall Wallace | Diane Lane, John Malkovich, Dylan Walsh, James Cromwell, Kevin Connelly, Scott Glenn | Bio-pic, Drama | Walt Disney Pictures |
| Sex and the City 2 | Michael Patrick King | Sarah Jessica Parker, Kim Cattrall, Kristin Davis, Cynthia Nixon, John Corbett, Chris Noth, David Eigenberg, Evan Handler, Jason Lewis, Lynn Cohen | Romantic comedy | Warner Bros. Pictures, New Line Cinema Preceded by ' |
| She's Out of My League | Jim Field Smith | Jay Baruchel, Alice Eve, T. J. Miller, Mike Vogel, Nate Torrence, Krysten Ritter, Geoff Stults, Lindsay Sloane | Romantic comedy | Paramount Pictures, DreamWorks Pictures |
| Shrek Forever After | Mike Mitchell | Mike Myers, Eddie Murphy, Cameron Diaz, Antonio Banderas, Walt Dohrn, Julie Andrews, John Cleese | Family, Fantasy | DreamWorks Animation, Paramount Pictures Preceded by Shrek the Third |
| Shutter Island | Martin Scorsese | Leonardo DiCaprio, Mark Ruffalo, Ben Kingsley, Michelle Williams, Patricia Clarkson, Emily Mortimer, Ted Levine, John Carroll Lynch, Elias Koteas, Jackie Earle Haley, Max von Sydow | Crime thriller, Drama | Paramount Pictures Based on the novel of the same name by Dennis Lehane |
| Skyline | Brothers Strause | Eric Balfour, Scottie Thompson, Donald Faison, David Zayas, Brittany Daniel, Neil Hopkins | Sci-fi, Thriller | Universal Pictures, Relativity Media |
| Small Town Saturday Night | Ryan Craig | Chris Pine, Shawn Christian, John Hawkes, Bre Blair, Muse Watson, Robert Pine, Brent Briscoe, Lin Shaye | Drama | Direct-to-DVD |
| The Social Network | David Fincher | Jesse Eisenberg, Andrew Garfield, Justin Timberlake, Armie Hammer, Max Minghella, Brenda Song, Rooney Mara, Dustin Fitzsimons, Joseph Mazzello, Rashida Jones | Drama | Columbia Pictures, Relativity Media Adapted from The Accidental Billionaires by Ben Mezrich |
| Solitary Man | Brian Koppelman, David Levien | Michael Douglas, Mary-Louise Parker, Jenna Fischer, Jesse Eisenberg, Imogen Poots, Susan Sarandon, Danny DeVito | Dramedy | Anchor Bay Films, Millennium Films |
| Somewhere | Sofia Coppola | Stephen Dorff, Elle Fanning, Benicio del Toro, Michelle Monaghan, Chris Pontius, Simona Ventura | Drama | Focus Features |
| The Sorcerer's Apprentice | Jon Turteltaub | Nicolas Cage, Jay Baruchel, Alfred Molina, Teresa Palmer, Monica Bellucci | Adventure, Comedy, Fantasy | Walt Disney Pictures |
| Splice | Vincenzo Natali | Adrien Brody, Sarah Polley | Sci-fi | Warner Bros. Pictures |
| The Spy Next Door | Brian Levant | Jackie Chan, Amber Valletta, Madeline Carroll, Will Shadley, Magnús Scheving, Billy Ray Cyrus, George Lopez | Action comedy, Family | Lionsgate, Relativity Media |
| Step Up 3D | Jon Chu | Rick Malambri, Adam G. Sevani, Sharni Vinson, Alyson Stoner | Dance, Drama, Romance | Summit Entertainment, Touchstone Pictures Preceded by ' |
| Stone | John Curran | Robert De Niro, Edward Norton, Milla Jovovich | Thriller | Overture Films |
| The Sundowner | Steve Christolos | Jon Bendz, Tim Tomchak | documentary | |
| The Switch | Josh Gordon and Will Speck | Jennifer Aniston, Jason Bateman, Patrick Wilson, Jeff Goldblum, Juliette Lewis | Romantic comedy | Miramax Films Based on Baster by Jeffrey Eugenides |
| Takers | John Luessenhop | Matt Dillon, Paul Walker, Idris Elba, Jay Hernandez, Michael Ealy, Tip "T.I." Harris, Chris Brown, Hayden Christensen, Zoe Saldana | Action, Crime drama | Screen Gems |
| Tangled | Byron Howard, Nathan Greno | Mandy Moore, Zachary Levi, Donna Murphy, Brad Garrett, Ron Perlman, M. C. Gainey, Jeffrey Tambor, Peter Sallis, Paul F. Tompkins | Animated, Family | Walt Disney Pictures, Walt Disney Animation Studios |
| The Tempest | Julie Taymor | Helen Mirren, David Strathairn, Djimon Hounsou, Russell Brand, Reeve Carney, Tom Conti, Chris Cooper, Alan Cumming, Felicity Jones, Alfred Molina, Ben Whishaw | Romance | Touchstone Pictures, Miramax Films Based on The Tempest by William Shakespeare |
| Tibet in Song | Ngawang Choephel | traditional Tibetan folk music | Documentary | Premiered at the 2009 Sundance Film Festival |
| Tooth Fairy | Michael Lembeck | Dwayne Johnson, Ashley Judd, Billy Crystal, Julie Andrews, Stephen Merchant, Ryan Sheckler | Family, Fantasy | 20th Century Fox |
| The Town | Ben Affleck | Ben Affleck, Rebecca Hall, Jon Hamm, Blake Lively, Jeremy Renner, Titus Welliver, Pete Postlethwaite, Chris Cooper, Slaine | Crime drama | Warner Bros. Based on Prince of Thieves by Chuck Hogan |
| The Tourist | Florian Henckel von Donnersmarck | Johnny Depp, Angelina Jolie, Paul Bettany, Rufus Sewell, Timothy Dalton, Steven Berkoff | Dramedy, Thriller | Columbia Pictures Based on Anthony Zimmer by Jérôme Salle |
| Toy Story 3 | Lee Unkrich | Tom Hanks, Tim Allen, Joan Cusack, Ned Beatty, Don Rickles, Michael Keaton, Wallace Shawn, John Ratzenberger, Estelle Harris, John Morris, Jodi Benson, Laurie Metcalf, Blake Clark, Teddy Newton, Bud Luckey, Timothy Dalton, Lori Alan, Kristen Schaal, Jeff Garlin, Bonnie Hunt, John Cygan, Jeff Pidgeon, Whoopi Goldberg, Jack Angel, R. Lee Ermey, Jan Rabson, Richard Kind | Family | Walt Disney Pictures, Pixar Animation Studios Preceded by Toy Story and Toy Story 2 |
| ' | Joseph Kosinski | Jeff Bridges, Garrett Hedlund, Bruce Boxleitner, Michael Sheen, Olivia Wilde, Beau Garrett, John Hurt | Science fiction | Walt Disney Pictures Preceded by Tron |
| True Grit | Joel and Ethan Coen | Jeff Bridges, Matt Damon, Josh Brolin, Barry Pepper, Hailee Steinfeld | Western | Paramount Pictures Based on the novel of the same name by Charles Portis; Remake of 1969 film |
| Trust | David Schwimmer | Clive Owen, Catherine Keener, Liana Liberato, Viola Davis, Jason Clarke | Drama | Nu Image |
| Twelve | Joel Schumacher | Chace Crawford, Rory Culkin, Esti Ginzburg, Curtis "50 Cent" Jackson, Zoë Kravitz, Emily Meade, Ethan Peck, Emma Roberts, Charlie Saxton, Kiefer Sutherland, Ellen Barkin, Jermaine Crawford, Billy Magnussen, Nico Tortorella, Isiah Whitlock Jr. | Drama | Hannover House. Based on the novel of the same name by Nick McDonell. |
| Unstoppable | Tony Scott | Denzel Washington, Chris Pine, Rosario Dawson | Action thriller | 20th Century Fox |
| Valentine's Day | Garry Marshall | Jessica Alba, Kathy Bates, Jessica Biel, Bradley Cooper, Eric Dane, Patrick Dempsey, Héctor Elizondo, Jamie Foxx, Jennifer Garner, Topher Grace, Anne Hathaway, Ashton Kutcher, Queen Latifah, Taylor Lautner, George Lopez, Shirley MacLaine, Emma Roberts, Julia Roberts, Taylor Swift | Romantic comedy | New Line Cinema |
| Vampires Suck | Jason Friedberg and Aaron Seltzer | Matt Lanter, Chris Riggi, Jenn Proske, Anneliese van der Pol, Ken Jeong | Spoof | Regency Enterprises |
| Waiting for Superman | Davis Guggenheim | The analyzation of the failing American public education system. | Documentary | Paramount Vantage, Participant Media, Walden Media |
| ' | Oliver Stone | Michael Douglas, Shia LaBeouf, Josh Brolin, Carey Mulligan, Eli Wallach, Susan Sarandon, Frank Langella, Vanessa Ferlito, Charlie Sheen | Drama | 20th Century Fox Preceded by Wall Street |
| Welcome to the Rileys | Jake Scott | James Gandolfini, Kristen Stewart, Melissa Leo, Ally Sheedy | Drama | Samuel Goldwyn Films, Destination Films |
| What If... | Dallas Jenkins | Kevin Sorbo, Kristy Swanson, Debby Ryan, John Ratzenberger | Comedy-drama | Pure Flix Entertainment |
| What's Wrong with Virginia | Dustin Lance Black | Jennifer Connelly, Ed Harris, Emma Roberts, Carrie Preston, Toby Jones | Drama | TicTock Studios, Killer Films |
| When in Rome | Mark Steven Johnson | Kristen Bell, Josh Duhamel, Will Arnett, Jon Heder, Dax Shepard, Danny DeVito, Anjelica Huston | Romantic comedy | Touchstone Pictures |
| Why Did I Get Married Too? | Tyler Perry | Tyler Perry, Janet Jackson, Jill Scott, Malik Yoba, Richard T. Jones, Michael Jai White, Lamman Rucker, Sharon Leal, Tasha Smith, Denise Boutte, Keyshia Cole, Cicely Tyson, Louis Gossett, Jr. | Comedy-drama | Lionsgate Preceded by Why Did I Get Married? |
| Winnebago Man | Ben Steinbauer | The Jack Rebney-Winnebago outtakes internet phenomenon and its impact on people and the person itself. | Documentary | Kino International |
| Winter's Bone | Debra Granik | Jennifer Lawrence, John Hawkes, Kevin Breznahan, Dale Dickey, Garret Dillahunt, Sheryl Lee, Shelley Waggener, Laura Sweetser | Drama, Suspense thriller | Roadside Attractions. Based on the novel of the same name by Daniel Woodrell |
| The Wolfman | Joe Johnston | Benicio del Toro, Anthony Hopkins, Emily Blunt, Hugo Weaving | Horror | Universal Pictures, Relativity Media Based on the 1941 film of the same name |
| Wonderful World | Joshua Goldin | Matthew Broderick, Sanaa Lathan, Michael Kenneth Williams, Jodelle Ferland, Jesse Tyler Ferguson, Ally Walker, Philip Baker Hall | Comedy-drama, Romance | Magnolia Pictures |
| Yogi Bear | Eric Brevig | Dan Aykroyd, Justin Timberlake, Anna Faris, Tom Cavanagh, T. J. Miller | Family, Live-action | Warner Bros. Pictures Based on the characters created by Hanna-Barbera Productions |
| You Again | Andy Fickman | Kristen Bell, Jamie Lee Curtis, Sigourney Weaver, Odette Yustman, Kristin Chenoweth, Victor Garber, Betty White, Kyle Bornheimer, Christine Lakin, Cloris Leachman | Comedy | Touchstone Pictures |
| You Will Meet a Tall Dark Stranger | Woody Allen | Antonio Banderas, Josh Brolin, Anthony Hopkins, Gemma Jones, Freida Pinto, Lucy Punch, Naomi Watts | Dramedy | Sony Pictures Classics |
| Youth in Revolt | Miguel Arteta | Michael Cera, Portia Doubleday, Jean Smart, Mary Kay Place, Justin Long, Ray Liotta, Steve Buscemi, Zach Galifianakis, Ari Graynor, Fred Willard | Comedy-drama | Dimension Films Based on the novel of the same name by C. D. Payne |