List of European number-one hits of 2008
This is a list of the European Music & Media magazine's European Hot 100 Singles and European Top 100 Albums number-ones of 2008.
| Date | Song | Artist | Album | Artist |
| January 5 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| January 12 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| January 19 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| January 26 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| February 2 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| February 9 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| February 16 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| February 23 | "Apologize" | Timbaland featuring OneRepublic | Sleep Through the Static | Jack Johnson |
| March 1 | "Apologize" | Timbaland featuring OneRepublic | Thriller 25 | Michael Jackson |
| March 8 | "Bleeding Love" | Leona Lewis | Back to Black | Amy Winehouse |
| March 15 | "Apologize" | Timbaland featuring OneRepublic | Back to Black | Amy Winehouse |
| March 22 | "Bleeding Love" | Leona Lewis | Back to Black | Amy Winehouse |
| March 29 | "Mercy" | Duffy | Back to Black | Amy Winehouse |
| April 5 | "Bleeding Love" | Leona Lewis | Back to Black | Amy Winehouse |
| April 12 | "Bleeding Love" | Leona Lewis | Back to Black | Amy Winehouse |
| April 19 | "Bleeding Love" | Leona Lewis | Accelerate | R.E.M. |
| April 26 | "Mercy" | Duffy | Rockferry | Duffy |
| May 3 | "4 Minutes" | Madonna featuring Justin Timberlake | Rockferry | Duffy |
| May 10 | "4 Minutes" | Madonna featuring Justin Timberlake | Rockferry | Duffy |
| May 17 | "4 Minutes" | Madonna featuring Justin Timberlake | Hard Candy | Madonna |
| May 24 | "4 Minutes" | Madonna featuring Justin Timberlake | Hard Candy | Madonna |
| May 31 | "4 Minutes" | Madonna featuring Justin Timberlake | Hard Candy | Madonna |
| June 7 | "4 Minutes" | Madonna featuring Justin Timberlake | Hard Candy | Madonna |
| June 14 | "4 Minutes" | Madonna featuring Justin Timberlake | Rockferry | Duffy |
| June 21 | "Mercy" | Duffy | Rockferry | Duffy |
| June 28 | "Mercy" | Duffy | Rockferry | Duffy |
| July 5 | "Mercy" | Duffy | Viva la Vida or Death and All His Friends | Coldplay |
| July 12 | "Mercy" | Duffy | Viva la Vida or Death and All His Friends | Coldplay |
| July 19 | "American Boy" | Estelle featuring Kanye West | Viva la Vida or Death and All His Friends | Coldplay |
| July 26 | "All Summer Long" | Kid Rock | Viva la Vida or Death and All His Friends | Coldplay |
| August 2 | "All Summer Long" | Kid Rock | Viva la Vida or Death and All His Friends | Coldplay |
| August 9 | "All Summer Long" | Kid Rock | Viva la Vida or Death and All His Friends | Coldplay |
| August 16 | "All Summer Long" | Kid Rock | Viva la Vida or Death and All His Friends | Coldplay |
| August 23 | "I Kissed a Girl" | Katy Perry | Viva la Vida or Death and All His Friends | Coldplay |
| August 30 | "I Kissed a Girl" | Katy Perry | Viva la Vida or Death and All His Friends | Coldplay |
| September 6 | "I Kissed a Girl" | Katy Perry | Viva la Vida or Death and All His Friends | Coldplay |
| September 13 | "I Kissed a Girl" | Katy Perry | All Hope Is Gone | Slipknot |
| September 20 | "I Kissed a Girl" | Katy Perry | Viva la Vida or Death and All His Friends | Coldplay |
| September 27 | "I Kissed a Girl" | Katy Perry | Death Magnetic | Metallica |
| October 4 | "I Kissed a Girl" | Katy Perry | Death Magnetic | Metallica |
| October 11 | "I Kissed a Girl" | Katy Perry | Death Magnetic | Metallica |
| October 18 | "I Kissed a Girl" | Katy Perry | Death Magnetic | Metallica |
| October 25 | "I Kissed a Girl" | Katy Perry | Death Magnetic | Metallica |
| November 1 | "So What" | Pink | Death Magnetic | Metallica |
| November 8 | "So What" | Pink | Black Ice | AC/DC |
| November 15 | "Infinity 2008" | Guru Josh Project | Black Ice | AC/DC |
| November 22 | "Infinity 2008" | Guru Josh Project | Black Ice | AC/DC |
| November 29 | "Infinity 2008" | Guru Josh Project | Black Ice | AC/DC |
| December 6 | "If I Were a Boy" | Beyoncé | Safe Trip Home | Dido |
| December 13 | "If I Were a Boy" | Beyoncé | Chinese Democracy | Guns N' Roses |
| December 20 | "Womanizer" | Britney Spears | Circus | Britney Spears |
| December 27 | "Womanizer" | Britney Spears | Black Ice | AC/DC |