List of European number-one hits of 2010
This is a list of the European Music & Media magazine's European Hot 100 Singles and European Top 100 Albums number-ones of 2010.
| Date | Song | Artist | Album | Artist |
| January 2 | "Meet Me Halfway" | The Black Eyed Peas | I Dreamed a Dream | Susan Boyle |
| January 9 | "Meet Me Halfway" | The Black Eyed Peas | I Dreamed a Dream | Susan Boyle |
| January 16 | "Meet Me Halfway" | The Black Eyed Peas | The Fame | Lady Gaga |
| January 23 | "Bad Romance" | Lady Gaga | The Fame | Lady Gaga |
| January 30 | "Meet Me Halfway" | Black Eyed Peas | The Fame | Lady Gaga |
| February 6 | "Bad Romance" | Lady Gaga | The Fame | Lady Gaga |
| February 13 | "Tik Tok" | Kesha | The Fame | Lady Gaga |
| February 20 | "Tik Tok" | Kesha | The Fame | Lady Gaga |
| February 27 | "Tik Tok" | Kesha | Soldier of Love | Sade |
| March 6 | "Tik Tok" | Kesha | Soldier of Love | Sade |
| March 13 | "Tik Tok" | Kesha | Soldier of Love | Sade |
| March 20 | "Alors on danse" | Stromae | Soldier of Love | Sade |
| March 27 | "Tik Tok" | Kesha | Plastic Beach | Gorillaz |
| April 3 | "Alors on danse" | Stromae | A Curious Thing | Amy Macdonald |
| April 10 | "Alors on danse" | Stromae | A Curious Thing | Amy Macdonald |
| April 17 | "Alors on danse" | Stromae | A Curious Thing | Amy Macdonald |
| April 24 | "Telephone" | Lady Gaga featuring Beyoncé | The Fame | Lady Gaga |
| May 1 | "Telephone" | Lady Gaga featuring Beyoncé | The Fame | Lady Gaga |
| May 8 | "Alors on danse" | Stromae | Iron Man 2 | AC/DC |
| May 15 | "Alors on danse" | Stromae | Iron Man 2 | AC/DC |
| May 22 | "Alors on danse" | Stromae | Iron Man 2 | AC/DC |
| May 29 | "Alors on danse" | Stromae | Iron Man 2 | AC/DC |
| June 5 | "Alors on danse" | Stromae | Iron Man 2 | AC/DC |
| June 12 | "Alors on danse" | Stromae | The House | Katie Melua |
| June 19 | "Satellite" | Lena | To the Sea | Jack Johnson |
| June 26 | "Wavin' Flag " | K'Naan | Bionic | Christina Aguilera |
| July 3 | "Wavin' Flag " | K'Naan | The House | Katie Melua |
| July 10 | "Wavin' Flag " | K'Naan | Recovery | Eminem |
| July 17 | "California Gurls" | Katy Perry featuring Snoop Dogg | Recovery | Eminem |
| July 24 | "California Gurls" | Katy Perry featuring Snoop Dogg | Aphrodite | Kylie Minogue |
| July 31 | "California Gurls" | Katy Perry featuring Snoop Dogg | Recovery | Eminem |
| August 7 | "Waka Waka " | Shakira featuring Freshlyground | Recovery | Eminem |
| August 14 | "Waka Waka " | Shakira featuring Freshlyground | Recovery | Eminem |
| August 21 | "Waka Waka " | Shakira featuring Freshlyground | The Suburbs | Arcade Fire |
| August 28 | "Waka Waka " | Shakira featuring Freshlyground | Recovery | Eminem |
| September 4 | "Waka Waka " | Shakira featuring Freshlyground | The Final Frontier | Iron Maiden |
| September 11 | "Waka Waka " | Shakira featuring Freshlyground | The Final Frontier | Iron Maiden |
| September 18 | "We No Speak Americano" | Yolanda Be Cool & DCUP | Teenage Dream | Katy Perry |
| September 25 | "We No Speak Americano" | Yolanda Be Cool & DCUP | Teenage Dream | Katy Perry |
| October 2 | "We No Speak Americano" | Yolanda Be Cool & DCUP | A Thousand Suns | Linkin Park |
| October 9 | "Love the Way You Lie" | Eminem featuring Rihanna | Going Back | Phil Collins |
| October 16 | "Love the Way You Lie" | Eminem featuring Rihanna | Going Back | Phil Collins |
| October 23 | "Love the Way You Lie" | Eminem featuring Rihanna | Going Back | Phil Collins |
| October 30 | "Love the Way You Lie" | Eminem featuring Rihanna | Robbie Williams | |
| November 6 | "Love the Way You Lie" | Eminem featuring Rihanna | Come Around Sundown | Kings of Leon |
| November 13 | "Only Girl " | Rihanna | Come Around Sundown | Kings of Leon |
| November 20 | "Only Girl " | Rihanna | Greatest Hits | Bon Jovi |
| November 27 | "Only Girl " | Rihanna | Greatest Hits | Bon Jovi |
| December 4 | "Only Girl " | Rihanna | Loud | Rihanna |
| December 11 | "Only Girl " | Rihanna | Progress | Take That |