Portrait | Monarch
| Reign | Consort
| Parents, co-regents, and notes |
| Antiochus III the Great
| 200–187 BC | Laodice III
Euboea
|
- Son of Seleucus II Callinicus and Laodice II. He appointed his eldest son Antiochus, who preceded him in death, as co-king.
- Antiochus III's second wife is attested in the hostile work of Polybius and the story is debated.
|
| Seleucus IV Philopator | 187–175 BC | Laodice IV
|
- Son of Antiochus III and Laodice III. He married Laodice IV, his brother Antiochus' widow.
|
| Antiochus | 175–170 BC | |
- Son of Seleucus IV and Laodice IV. The minister Heliodorus held real power, then Antiochus was made co-king by his uncle Antiochus IV.
|
| Antiochus IV Epiphanes | 175–164 BC | Laodice IV
|
- Son of Antiochus III and Laodice III. Married his brother's widow.
|
| Antiochus V Eupator | 164–162 BC | Unmarried |
- Son of Antiochus IV Epiphanes and possibly Laodice IV. His regent Lysias held actual power.
|
| Demetrius I Soter | 162–150 BC | |
|
| Antiochus | 150 BC | | Known from a coin minted in the same year Demetrius I lost his throne; his identity is left to speculations. |
| Alexander I Balas | 150–145 BC | Cleopatra Thea
|
- Claimed to be a son of Antiochus IV. He could have been an illegitimate son of Antiochus by a concubine named Antiochis.
|
| Demetrius II Nicator | 145–138 BC
| Cleopatra Thea
|
- Son of Demetrius I and possibly Laodice V.
- First reign; Ptolemy VI Philometor of Egypt divorced his daughter Cleopatra Thea from Alexander I and married her to Demetrius.
|
| Antiochus VI Dionysus | 144–142/141 BC | |
- Son of Alexander I and Cleopatra Thea. Was proclaimed king against Demetrius II by general Diodotus Tryphon who held actual power and eventually killed Antiochus.
|