List of autoimmune diseases
This list of autoimmune diseases is categorized by organ and tissue type to help locate diseases that may be similar.
Autoimmune diseases qualifiers
Overview of the qualifiers for the list.Autoimmune diseases
Major organs
Glands
Digestive system
Tissue
Autoimmune comorbidities
This list includes conditions that are not diseases but signs common to autoimmune disease. Some, such as chronic fatigue syndrome, are controversial. These conditions are included here because they are frequently listed as autoimmune diseases but should not be included in the list above until there is more consistent [|evidence].| Organ/Tissue Type Disease Name | Level of Acceptance for Autoimmunity | Hypersensitivity | ICD-9 Codes | Notes/Autoantibodies/Synonyms |
| Chronic fatigue syndrome | Comorbidity, N | Symptomatic of autoimmune diseases or autoimmune activity, but not a disease or a cause of disease. | ||
| Complex regional pain syndrome | Comorbidity, N | Symptomatic of autoimmune diseases or autoimmune activity, but not a disease or a cause of disease. Synonyms: Amplified Musculoskeletal Pain Syndrome, Reflex Neurovascular Dystrophy, Reflex sympathetic dystrophy | ||
| Eosinophilic esophagitis | Comorbidity, N | |||
| Gastritis | Comorbidity, Y | Possibly symptomatic of autoimmune diseases, but not a disease or a cause of disease. Autoantibodies: serum antiparietal and anti-IF antibodies. | ||
| Interstitial lung disease | Comorbidity, N | Associated with several autoimmune connective tissue diseases. | ||
| POEMS syndrome | Comorbidity, Y | Possibly symptomatic of autoimmune diseases, but not a disease or a cause of disease. Autoantibodies: interleukin 1β, interleukin 6 and TNFα. vascular endothelial growth factor, given the.. | ||
| Raynaud's phenomenon | Comorbidity, S | Symptomatic of autoimmune diseases or autoimmune activity, but not a disease or a cause of disease. | ||
| Primary immunodeficiency | Comorbidity, N | The condition is inherited, but it is associated with several autoimmune diseases. | ||
| Pyoderma gangrenosum | Comorbidity, Y | Possibly symptomatic of autoimmune diseases, but not a disease or a cause of disease. |
Non-autoimmune
At this time, there is not sufficient evidence—direct, indirect, or circumstantial—to indicate that these diseases are caused by autoimmunity. These conditions are included here because:- The disease was listed in the prior version of this table
- The disease is included in several widely used lists of autoimmune disease and is shown here to ensure that a person visiting this page does not conclude that the disease was not considered. Before moving a condition from here to the list of autoimmune diseases, references should be provided in the Wikipedia page for the condition that point to evidence, direct or indirect, that it is an autoimmune disease.
| Organ/Tissue Type Disease Name | Level of Acceptance for Autoimmunity | Hypersensitivity | ICD-9 Codes | Notes/Autoantibodies/Synonyms |
| Agammaglobulinemia | Not Autoimmune, Y | An immune system disorder but not an autoimmune disease.. Autoantibodies: IGHM; IGLL1: CD79A; CD79B; BLNK; LRRC8A. | ||
| Amyloidosis | Not Autoimmune, N | No consistent evidence of association with autoimmunity. | ||
| Amyotrophic lateral sclerosis | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: Amyotrophic lateral sclerosis. | ||
| Anti-tubular basement membrane nephritis | Not Autoimmune, N | No consistent evidence of association with autoimmunity. | ||
| Atopic allergy | Not Autoimmune, Y | I | A hypersensitivity. | |
| Atopic dermatitis | Not Autoimmune, Y | I | A hypersensitivity. | |
| Autoimmune peripheral neuropathy | Not Autoimmune, F, A | A symptom of many diseases, including some that may be autoimmune. Not an autoimmune disease. | ||
| Blau syndrome | Not Autoimmune, Y | Overlaps both sarcoidosis and granuloma annulare. No evidence of association with autoimmunity. | ||
| Cancer | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. | ||
| Castleman's disease | Not Autoimmune, Y | An immune system disorder but not an autoimmune disease.. Autoantibodies: Over expression of IL-6. | ||
| Chagas disease | Not Autoimmune, S | No consistent evidence of association with autoimmunity. | ||
| Chronic obstructive pulmonary disease | Not Autoimmune, S | No consistent evidence of association with autoimmunity. | ||
| Chronic recurrent multifocal osteomyelitis | Not Autoimmune, Y | LPIN2, D18S60. Synonyms: Majeed syndrome | ||
| Complement component 2 deficiency | Not Autoimmune, Y | Possibly symptomatic of autoimmune diseases, but not a disease. | ||
| Congenital heart block | Not Autoimmune, N | May be related to autoimmune activity in the mother. | ||
| Contact dermatitis | Not Autoimmune, Y | IV | A hypersensitivity. | |
| Cushing's syndrome | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. | ||
| Cutaneous leukocytoclastic angiitis | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: neutrophils. | ||
| Dego's disease | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. | ||
| Eczema | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: LEKTI, SPINK5, filaggrin., Brain-derived neurotrophic factor and Substance P.. | ||
| Eosinophilic gastroenteritis | Not Autoimmune, Y | Possibly a hypersensitivity. Autoantibodies: IgE, IL-3, IL-5, GM-CSF, eotaxin. | ||
| Eosinophilic pneumonia | Not Autoimmune, F, Y | A class of diseases, some of which may be autoimmune. Specifically, Churg-Strauss syndrome, a subtype of Eosinophilic pneumonia, is autoimmune. | ||
| Erythroblastosis fetalis | Not Autoimmune, Y | II | Mother's immune system attacks fetus. An immune system disorder but not autoimmune. Autoantibodies: ABO, Rh, Kell antibodies. | |
| Fibrodysplasia ossificans progressiva | Not Autoimmune, Y | Possibly an immune system disorder but not autoimmune. Autoantibodies: ACVR1 Lymphocytes express increased BMP4. | ||
| Gastrointestinal pemphigoid | Not Autoimmune, A | No consistent evidence of association with autoimmunity. | ||
| Hypogammaglobulinemia | Not Autoimmune, Y | An immune system disorder but not autoimmune. Autoantibodies: IGHM, IGLL1, CD79A, BLNK, LRRC8A, CD79B. | ||
| Idiopathic giant-cell myocarditis | Not Autoimmune, N | No consistent evidence of autoimmune cause though the disease has been found comorbid with other autoimmune diseases. Synonyms: Giant cell myocarditis | ||
| Idiopathic pulmonary fibrosis | Not Autoimmune, Y | Autoantibodies: SFTPA1, SFTPA2, TERT, and TERC.. Synonyms: Fibrosing alveolitis | ||
| IgA nephropathy | Not Autoimmune, Y | III? | Autoantibodies: IgA produced from marrow rather than MALT. Synonyms: IgA nephrits, Berger's disease, Synpharyngitic Glomerulonephritis. An immune system disorder but not an autoimmune disease. | |
| Immunoregulatory lipoproteins | Not Autoimmune, N | Not a disease. | ||
| IPEX syndrome | Not Autoimmune, N | A genetic mutation in FOXP3 that leads to autoimmune diseases, but no consistent evidence that it is an autoimmune disorder itself.. Synonyms: X-linked polyendocrinopathy, immunodeficiency and diarrhea-syndrome | ||
| Ligneous conjunctivitis | Not Autoimmune, N | No consistent evidence of association with autoimmunity. | ||
| Majeed syndrome | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: LPIN2. | ||
| Narcolepsy | Not Autoimmune, Y | II? | No evidence of association with autoimmunity. Research not reproducible. Autoantibodies: hypocretin or orexin, HLA-DQB1*0602. | |
| Rasmussen's encephalitis | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: anti-NR2A antibodies. | ||
| Schizophrenia | Not Autoimmune, S | No consistent evidence of association with autoimmunity. | ||
| Serum sickness | Not Autoimmune, Y | III | A hypersensitivity. | |
| Spondyloarthropathy | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: HLA-B27. | ||
| Sweet's syndrome | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. Autoantibodies: GCSF. | ||
| Takayasu's arteritis | Not Autoimmune, Y | No consistent evidence of association with autoimmunity. | ||
| Undifferentiated spondyloarthropathy | Not Autoimmune, Y | See Enthesitis-related arthritis. |