List of number-one dance singles of 2015 (U.S.)
This is a list of the United States Billboard Dance Club Songs number one hits of 2015.
| Indicates most-played song of 2015. |
| Issue date | Song | Artist | Ref. |
| January 3 | "Rolling in the Deep " | Aretha Franklin | |
| January 10 | "Jealous" | Nick Jonas | |
| January 17 | "Big Fun" | D.O.N.S. and Terri B! | |
| January 24 | "Go All Night" | Gorgon City featuring Jennifer Hudson | |
| January 31 | "Uptown Funk" | Mark Ronson featuring Bruno Mars | |
| February 7 | "Blind Heart" | Cazzette featuring Terri B! | |
| February 14 | "7/11" | Beyoncé | |
| February 21 | "All of You" | Betty Who | |
| February 28 | "Right Now" | Mary J. Blige | |
| March 7 | "Living for Love" | Madonna | |
| March 14 | "Time of Our Lives" | Pitbull and Ne-Yo | |
| March 21 | "Something New" | Axwell and Ingrosso | |
| March 28 | "I'm Gonna Get You" | Dave Audé featuring Jessica Sutta | |
| April 4 | "Elastic Heart" | Sia | |
| April 11 | "Crazy" | Erika Jayne featuring Maino | |
| April 18 | "Right Here, Right Now" | Giorgio Moroder featuring Kylie Minogue | |
| April 25 | "Talking Body" | Tove Lo | |
| May 2 | "Free People" | Tony Moran featuring Martha Wash | |
| May 9 | "Heartbeat Song" | Kelly Clarkson | |
| May 16 | "One Hot Mess" | Malea | |
| May 23 | "Chains" | Nick Jonas | |
| May 30 | "Ghosttown" | Madonna | |
| June 6 | "The Giver " | Duke Dumont | |
| June 13 | "Insomnia" | Audien featuring Parson James | |
| June 20 | "I'll Be There" | Chic featuring Nile Rodgers | |
| June 27 | "Bitch Better Have My Money" | Rihanna | |
| July 4 | "Mr. Put It Down" | Ricky Martin featuring Pitbull | |
| July 11 | "House on Fire" | Ryan Cabrera | |
| July 18 | "Pretty Girls" | Britney Spears and Iggy Azalea | |
| July 25 | "This Feeling" | L'Tric | |
| August 1 | "Déjà Vu" | Giorgio Moroder featuring Sia | |
| August 8 | "Honey, I'm Good." | Andy Grammer | |
| August 15 | "Bitch I'm Madonna" | Madonna featuring Nicki Minaj | |
| August 22 | "Kiss Me Quick" | Nathan Sykes | |
| August 29 | "Beautiful Now" | Zedd featuring Jon Bellion | |
| September 5 | "Holding On" | Disclosure featuring Gregory Porter | |
| September 12 | "Cool for the Summer" | Demi Lovato | |
| September 19 | "Emergency" | Icona Pop | |
| September 26 | "Something Better" | Audien featuring Lady Antebellum | |
| October 3 | "There Must Be Love" | David Morales and Janice Robinson | |
| October 10 | "Omen" | Disclosure featuring Sam Smith | |
| October 17 | "Feel the Vibe" | Bob Sinclar featuring Dawn Tallman | |
| October 24 | "OXO" | Olivia Somerlyn | |
| October 31 | "What Do You Mean?" | Justin Bieber | |
| November 7 | "The Other Boys" | Nervo featuring Kylie Minogue, Jake Shears and Nile Rodgers | |
| November 14 | "Synergy" | Sted-E, Hybrid Heights and Crystal Waters | |
| November 21 | "You Have to Believe" | Dave Audé featuring Olivia Newton-John and Chloe Lattanzi | |
| November 28 | "Ocean Drive" | Duke Dumont | |
| December 5 | "Insomnia 2.0" | Faithless | |
| December 12 | "Levels" | Nick Jonas | |
| December 19 | "Confident" | Demi Lovato | |
| December 26 | "Hello" | Adele |