List of number-one digital songs of 2005 (U.S.)
The highest-selling digital singles in the United States are ranked in the Hot Digital Songs chart, published by Billboard magazine. The data are compiled by Nielsen SoundScan based on each single's weekly digital sales, which combines sales of different versions of a single for a summarized figure.
Chart history
| Issue date | Song | Artist | Weekly sales | Ref |
| January 22 | "Boulevard of Broken Dreams" | Green Day | ||
| January 29 | "Boulevard of Broken Dreams" | Green Day | ||
| February 5 | "Boulevard of Broken Dreams" | Green Day | ||
| February 12 | "Boulevard of Broken Dreams" | Green Day | 31,000 | |
| February 19 | "Candy Shop" | 50 Cent featuring Olivia | 40,000 | |
| February 26 | "Candy Shop" | 50 Cent featuring Olivia | ||
| March 5 | "Candy Shop" | 50 Cent featuring Olivia | 55,500 | |
| March 12 | "Candy Shop" | 50 Cent featuring Olivia | 50,500 | |
| March 19 | "Candy Shop" | 50 Cent featuring Olivia | 48,000 | |
| March 26 | "Candy Shop" | 50 Cent featuring Olivia | 47,500 | |
| April 2 | "Candy Shop" | 50 Cent featuring Olivia | ||
| April 9 | "Candy Shop" | 50 Cent featuring Olivia | ||
| April 16 | "Switch" | Will Smith | 40,000 | |
| April 23 | "Beverly Hills" | Weezer | 40,500 | |
| April 30 | "Hollaback Girl" | Gwen Stefani | ||
| May 7 | "Hollaback Girl" | Gwen Stefani | 58,500 | |
| May 14 | "Hollaback Girl" | Gwen Stefani | ||
| May 21 | "Hollaback Girl" | Gwen Stefani | 61,500 | |
| May 28 | "Hollaback Girl" | Gwen Stefani | ||
| June 4 | "Hollaback Girl" | Gwen Stefani | ||
| June 11 | "Hollaback Girl" | Gwen Stefani | ||
| June 18 | "Hollaback Girl" | Gwen Stefani | ||
| June 25 | "Don't Phunk With My Heart" | The Black Eyed Peas | ||
| July 2 | "Don't Phunk With My Heart" | The Black Eyed Peas | ||
| July 9 | "Don't Phunk With My Heart" | The Black Eyed Peas | ||
| July 16 | "Hollaback Girl" | Gwen Stefani | ||
| July 23 | "These Boots Are Made for Walkin'" | Jessica Simpson | 43,000 | |
| July 30 | "Pon de Replay" | Rihanna | ||
| August 6 | "Pon de Replay" | Rihanna | ||
| August 13 | "Pon de Replay" | Rihanna | ||
| August 20 | "Pon de Replay" | Rihanna | ||
| August 27 | "Pon de Replay" | Rihanna | ||
| September 3 | "Just the Girl" | The Click Five | 43,000 | |
| September 10 | "Just the Girl" | The Click Five | ||
| September 17 | "Gold Digger" | Kanye West featuring Jamie Foxx | 80,500 | |
| September 24 | "Gold Digger" | Kanye West featuring Jamie Foxx | 77,000 | |
| October 1 | "Gold Digger" | Kanye West featuring Jamie Foxx | ||
| October 8 | "Gold Digger" | Kanye West featuring Jamie Foxx | 69,500 | |
| October 15 | "Photograph" | Nickelback | 77,000 | |
| October 22 | "Gold Digger" | Kanye West featuring Jamie Foxx | ||
| October 29 | "Gold Digger" | Kanye West featuring Jamie Foxx | ||
| November 5 | "Gold Digger" | Kanye West featuring Jamie Foxx | ||
| November 12 | "Gold Digger" | Kanye West featuring Jamie Foxx | ||
| November 19 | "Gold Digger" | Kanye West featuring Jamie Foxx | 49,500 | |
| November 26 | "My Humps" | Black Eyed Peas | ||
| December 3 | "Hung Up" | Madonna | 45,500 | |
| December 10 | "Hung Up" | Madonna | ||
| December 17 | "When I'm Gone" | Eminem | 46,000 | |
| December 24 | "All I Want for Christmas Is You" | Mariah Carey | 41,000 | |
| December 31 | "Don't Forget About Us" | Mariah Carey | 39,000 |