List of number-one singles of 1988 (Ireland)
This is a list of singles which have reached number one on the Irish Singles Chart in 1988.
| Week ending | Song | Artist |
| 2 January | "Fairytale of New York" | The Pogues featuring Kirsty MacColl |
| 9 January | "Fairytale of New York" | The Pogues featuring Kirsty MacColl |
| 16 January | "Heaven is a Place on Earth" | Belinda Carlisle |
| 23 January | "Sign Your Name" | Terence Trent D'Arby |
| 30 January | "I Think We're Alone Now" | Tiffany |
| 6 February | "I Think We're Alone Now" | Tiffany |
| 13 February | "When Will I Be Famous" | Bros |
| 20 February | "Get Outta My Dreams, Get into My Car" | Billy Ocean |
| 27 February | "I Should Be So Lucky" | Kylie Minogue |
| 5 March | "I Should Be So Lucky" | Kylie Minogue |
| 12 March | "Together Forever" | Rick Astley |
| 19 March | "Feet on the Ground" | Hothouse Flowers  |
| 26 March | "Drop the Boy" | Bros |
| 2 April | "Could've Been" | Tiffany |
| 9 April | "Heart" | Pet Shop Boys |
| 16 April | "Heart" | Pet Shop Boys |
| 23 April | "Heart" | Pet Shop Boys |
| 30 April | "One More Try" | George Michael |
| 7 May | "Perfect" | Fairground Attraction |
| 14 May | "Perfect" | Fairground Attraction |
| 21 May | "With a Little Help from My Friends" | Wet Wet Wet |
| 28 May | "With a Little Help from My Friends" | Wet Wet Wet |
| 4 June | "With a Little Help from My Friends" | Wet Wet Wet |
| 11 June | "The Boys in Green" | Republic of Ireland Soccer Squad |
| 18 June | "The Boys in Green" | Republic of Ireland Soccer Squad |
| 25 June | "The Boys in Green" | Republic of Ireland Soccer Squad |
| 2 July | "The Boys in Green" | Republic of Ireland Soccer Squad |
| 9 July | "Fast Car" | Tracy Chapman |
| 16 July | "Nothing's Gonna Change My Love for You" | Glenn Medeiros |
| 23 July | "Nothing's Gonna Change My Love for You" | Glenn Medeiros |
| 30 July | "Nothing's Gonna Change My Love for You" | Glenn Medeiros |
| 6 August | "Flight of Earls" | Paddy Reilly |
| 13 August | "The Locomotion" | Kylie Minogue |
| 20 August | "The Only Way Is Up" | Yazz and the Plastic Population |
| 27 August | "The Only Way Is Up" | Yazz and the Plastic Population |
| 3 September | "The Harder I Try" | Brother Beyond |
| 10 September | "A Groovy Kind of Love" | Phil Collins |
| 17 September | "A Groovy Kind of Love" | Phil Collins |
| 24 September | "Desire" | U2 |
| 1 October | "Desire" | U2 |
| 8 October | "Desire" | U2 |
| 15 October | "Desire" | U2 |
| 22 October | "Orinoco Flow " | Enya |
| 29 October | "Orinoco Flow " | Enya |
| 5 November | "Orinoco Flow " | Enya |
| 12 November | "Orinoco Flow " | Enya |
| 19 November | "Stand Up for Your Love Rights" | Yazz and the Plastic Population |
| 26 November | "First Time" | Robin Beck |
| 3 December | "Missing You" | Chris de Burgh |
| 10 December | "Mistletoe and Wine" | Cliff Richard |
| 17 December | "Mistletoe and Wine" | Cliff Richard |
| 24 December | "Mistletoe and Wine" | Cliff Richard |
| 31 December | "Mistletoe and Wine" | Cliff Richard |
- 29 Number Ones
- Most weeks at No.1 : "The Boys in Green" - Republic of Ireland Soccer Squad, "Desire" - U2, "Orinoco Flow " - Enya, "Mistletoe and Wine" - Cliff Richard
- Most weeks at No.1 : Republic of Ireland Soccer Squad, U2, Enya, Cliff Richard
- Most No.1s: Tiffany, Bros, Kylie Minogue, Yazz