List of people from Pathanamthitta district

Politicians and political activists

• K. Kumar – President of the Travancore Congress Committee/KPCC, AICC working Committee Member, Translator of Mahatma Gandhi during his Kerala tours Veteran Freedom Fighter, Gandhian Reformer and Journalist who participated in most of the major agitations for Indian freedom. Also known as 'Elanthur Gandhi' and 'Travancore Kumar'.
• Pandalam Kerala Varma – poet
• Pandalam Sudhakaran – former Minister
• K. K. Nair – founder of Pathanamthitta district and MLA representing the district 34 years
• Adoor Prakash – Ex Revenue Minister
• Mathew T. Thomas – former Transport Minister
• Pandalam KP
• Thadiyil Raghavan Pillai
• Khadar Das Gopala Pillai

  Judiciary

• Justice M. Fathima Beevi – first woman on the Supreme Court of India

  Spiritual leaders

• Baselios Thoma Didymos I, Catholicos of the East and Malankara Metropolitan
• Geevarghese Mar Ivanios
• V. C. Samuel, World Council of Churches
• Thomas Mar Athanasius
• Kuriakose Mar Clemis
• Nitya Chaitanya Yati
• Abraham Mar Thoma
• Juhanon Mar Thoma
• Alexander Mar Thoma
• Philipose Mar Chrysostom
• Joseph Mar Thoma
• Yuhanon Mor Militos
• Sadhu Kochu Kunju Upadesi
• Baselios Cleemis

  Writers

• Mahakavi Pandalam Kerala Varma – poet, Daivame kaithozham kaakkumarakenam – is written by Keralavarma.
• Kadammanitta Ramakrishnan
• Benyamin – Kerala Sahitya Akademi award winner
• Muloor S. Padmanabha Panicker
• Vennikulam Gopalakurup – poet
• P. K. Gopi – poet

  Artists , painters and cartoonists

• V. S. Valiathan – Classical Painter and Winner of Raja Ravi Varma Puraskaram.
• P. K. Manthri – Political Cartoonist and Creator of Cartoon characters Pachuvum Gopalanum
• C. K. Ra –Painter
• Jitheshji - World's Fastest Cartoonist and Initiator of the art genre Varayarangu
• Madhu Omalloor –was the Staff Cartoonist of Deshabhimani
• Paris Viswanathan- Painter

  Film and stage

• Mohanlal – actor
• Thilakan – actor
• Adoor Gopalakrishnan – film director
• K. G. George – film director
• B. Unnikrishnan – film director
• Blessy – film director
• Captain Raju – actor, director, producer
• Aju Varghese – actor
• Kailash – actor
• Dr. Rajiv Pillai – actor
• Sidhartha Siva – actor, director
• Kaviyoor Sivaprasad – director, screenwriter
• Adoor Bhasi – actor
• M.G. Soman – actor
• Prathapachandran – actor
• Nayantara – actress
• Meera Jasmine – actress
• Parvathy Jayaram – actress
• Samyuktha Varma – actress
• Mythili – actress
• Urmila Unni – actress
• Utthara Unni – actress
• Kaveri – actress
• Kaviyoor Ponnamma – actress
• Aranmula Ponnamma – actress
• KPAC Lalitha – actress
• Adoor Bhavani – actress
• Adoor Pankajam – actress

  Kathakali, Padayani and other performing artists

• Kadammanitta Vasudevan Pillai – Padayani Exponent
• C. J. Kuttappan – former Chairman of Folklore Academy

  Journalists

• T. J. S. George – senior journalist and Kerala Sahitya Akademi Award Winner
• George Varghese – director of Prasar Bharati
• Elanthoor Kumarji – veteran freedom activist who revived and edited the government-banned "Swadeshabhimani" newspaper run by Swadeshabhimani Ramakrishna Pillai in early twenties to kindle the spirit of freedom movement in the erstwhile Travancore State – also known as 'Elanthoor Gandhi' and 'Travancore Kumar'

  Others

• M. George Muthoot
• George Alexander Muthoot