Liver receptor homolog-1
The liver receptor homolog-1 also known as NR5A2 is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of the nuclear receptor family of intracellular transcription factors.
LRH-1 plays a critical role in the regulation of development, cholesterol transport, bile acid homeostasis and steroidogenesis.
LRH-1 is important for maintaining pluripotence of stem cells during embryonic development.Interactions
Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.
