Born to Charles Louis de Lorraine, Count of Marsan, Prince of Mortagne, and his wife Élisabeth de Roquelaure, she was the second of four children. Her younger brother, GastonJean Baptiste Charles, was the husband of Marie Louise de Rohan, future governess of Louis XVI and his siblings. Gaston died of Smallpox aged twenty two. Her younger brother was Camille, Prince of Marsan. She was known simply as Louise. Styled Mademoiselle de Marsan prior to her marriage, as a male line descendant of the House of Lorraine she was entitled to the style of Highness. She was a Canoness of the prestigious Remiremont Abbey in Remiremont, in the Vosges in Lorraine. Remiremont had been closely related to the Lorraine's for centuries. She was nominated as Canoness in 1733. She was engaged toGodefroy de La Tour d'Auvergne, only son and heir of Charles Godefroy de La Tour d'Auvergne and his Polish born wife Maria Karolina Sobieska. The couple were married on 27 November 1743. Her husband, as heir to the Duchy of Bouillon, was styled prince de Turenne; as such, Louise became the Princess of Turenne. The couple's marriage was carried out by the Cardinal d'Avergne, her husband's cousin; they wed in the Hôtel of her younger brother, Louis Camille de Lorraine. Her husband was nine years younger than she. The couple were the parents of four children, two of which survived infancy. At the death of her father in law Charles Godefroy de La Tour d'Auvergne, her husband became the Duke of Bouillon. She died in at the Hôtel de Lordat in Paris aged 69 over the night of 4–5 September 1788. The year after her death, her husband married again; to Marie Françoise Henriette de Banastre, a girl some forty-seven years younger than he and a daughter of one of his footmen. Her brother Camille, Prince of Marsan also died at the Hôtel de Bouillon in 1780. She was buried at the Église Saint-Sulpice, Paris|Church of Saint-Sulpice in Paris on 9 September. At her husband's death in 1792, her son succeeded. Her son had no children and thus the House of La Tour d'Auvergne became extinct. She has no known surviving descendants; the Princes of Guéméné claim the Duchy of Bouillon via Louise's sister in lawMarie Louise de La Tour d'Auvergne who married the Prince of Guéméné and has descendants in modern Austria.