Henrique began his professional MMA career in November 2011. He competed exclusively in his native Brazil for the first three-and-a-half years of his career and amassed a record of 8-1 with one No Contest over this time.
Henrique made his promotional debut against fellow newcomer Francis Ngannou on December 19, 2015 at UFC on Fox 17. He lost the fight via knockout in the second round. Henrique faced promotional newcomer Dmitrii Smolyakov on July 23, 2016 at UFC on Fox 20. He won the fight via submission in the second round. Henrique next faced Christian Colombo on November 19, 2016 at UFC Fight Night 100. He won the fight via submission in the third round. Henrique faced Marcin Tybura on March 5, 2017 at UFC 209. He lost the fight via TKO in the third round. Henrique faced promotional newcomer Arjan Bhullar on September 9, 2017 at UFC 215. He lost the fight via unanimous decision. Henrique was expected to face Timothy Johnson at UFC Fight Night 125, but was removed from the fight card due to a bicep injury that needed surgery. In June 2018 it was announced that Henrique would face Mark Godbeer in a light heavyweight bout on September 22, 2018 at UFC Fight Night 137. However, Godbeer pulled out of the fight in early August citing injury and was replaced by promotional newcomer Ryan Spann. He lost the fight via a unanimous decision. It was reported on November 24, 2018 that Henrique was released by UFC.
Post-UFC career
After the release from the UFC Henrique one submission victory in his old promotion Watch Out Combat Show before signing with the KSW. Henrique made his promotional debut against Michał Andryszak at on May 18, 2018. He won the fight via first-round submission. Henrique made his sophomore appearance in the KSW as he replaced Damian Grabowski who withdrew from a title bout against Philip De Fries at on September 14, 2019 due to a hand injury. Henrique lost the fight split decision. After the failed title shot, Henrique was expected to face Teodoras Aukštuolis at ARES FC 2 on April 3, 2020. However, due to the COVID-19 pandemic, the event was postponed until October 30, 2020.