Miles was born in Lachute, Louisiana. Except for a period of service in the United States Navy in 1943 and 1944, he worked on a cotton plantation until the early 1950s and listened to blues musicon the radio. Suitably inspired, Miles moved to Houston, Texas, in 1952, with the single aim of meeting Lightnin' Hopkins. Miles stated, "I went to Houston for one reason. I went to see Lightnin’ Hopkins. That's what I went for and that's what I did. Lightnin' Hopkins taught me just about everything about blues singing. The first time I ever sang in front of an audience was in 1952 with Lightnin'. The first day I met Lightnin' he named me "Long Gone" … and I've been Long Gone Miles ever since". According to Ed Pearl, "Miles appeared on Lightnin's doorstep in Houston a long while back, and Lightnin' wanted to close the door. And Luke proceeded to just go to sleep on his doorstep.... he was a real country guy. So Lightnin' took a fancy to him and let him hang around and he was a good singer, and Lightnin' sometimes let him perform with him on stage". Nervous at his first concert, Miles dropped the microphone. However, he persevered and played at local clubs, and he subsequently appeared on several of Hopkins's recordings, including the "live album", Country Blues. In 1961, Miles relocated to Los Angeles, but, with Hopkins being "rediscovered" and his career booming, the two parted ways. In 1962, Miles recorded two singles for Smash Records, accompanied by Brownie McGhee and Sonny Terry. The B-side to both singles was the antiwar song "War Time Blues", in which Miles sang, "Well, when I get my examination card, I want the doctortell me I too doggone old". Also in 1962, he teamed up with the guitarist Willie Chambers, and they performed together regularly for two years. In 1964, Miles recorded the albumCountry Born, released by World Pacific. In addition, he recorded singles for Two Kings Records in 1965 and, four years later, another one, "Hello Josephine", for Kent. A live recording of Miles was made in 1966 at the Ash Grove nightclub, in Los Angeles, where he was accompanied on acoustic guitar by Bernie Pearl, the brother of the Ash Grove proprietor, Ed Pearl. However, in 1970, Miles lived up to his stage name and disappeared for a long time from performing and recording. He never spoke to or heard from Hopkins again. The later album releases were Country Boy, which included mainly previously unreleased tracks recorded in 1962, and Riding Around in My V8 Ford, composed of tracks recorded live in Venice, California, in 1985. Miles died on November 22, 1987, in Los Angeles, aged 62.