MAST2


Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene. The protein encoded by this gene controls TRAF6 and NF-kappaB activity.

Interactions

MAST2 has been shown to interact with PCLKC.

Model organisms

s have been used in the study of MAST2 function. A conditional knockout mouse line called Mast2tm1aWtsi has been generated. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping