MRC-5


MRC-5 is a diploid human cell culture line composed of fibroblasts, originally developed from research deriving lung tissue of a 14 week old aborted Caucasian male fetus. The cell line was isolated by J.P. Jacobs and colleagues in September 1966 from the seventh population doubling of the original strain, and MRC-5 cells themselves are known to reach senescence in around 45 population doublings.

Applications

MRC-5 cells are currently used to produce several vaccines including for MMR, varicella and polio.