Macroglobulin


A macroglobulin is a plasma globulin of high molecular weight.
Elevated levels of macroglobulins may cause manifestations of excess blood viscosity and/or precipitate within blood vessels when temperature drops.
Other macroglobulins include alpha-2 macroglobulin, which is elevated in nephrotic syndrome, diabetes, severe burns, and other conditions, while a deficiency is associated with chronic obstructive pulmonary disease.