Malate dehydrogenase (oxaloacetate-decarboxylating)
In enzymology, a malate dehydrogenase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are -malate and NAD+, whereas its 3 products are pyruvate, CO2, and NADH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is -malate:NAD+ oxidoreductase . Other names in common use include malic enzyme, pyruvic-malic carboxylase, NAD+-specific malic enzyme, NAD+-malic enzyme, and NAD+-linked malic enzyme. This enzyme participates in pyruvate metabolism.As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,,,,,, and.
